Physical Health


What is mononucleosis?

Infectious mononucleosis, commonly called "mono," is a disease caused by the Epstein-Barr virus (EBV). EBV is one of the most common viruses worldwide. Most people are exposed to EBV as children, but the infection often goes unnoticed because they experience minimal symptoms. The majority of people have been exposed to EBV by the age of 35 and have developed immunity. However, when EBV infection occurs during late adolescence or early adulthood, there is a 35% to 50% chance of developing mono. 

Is it common?

As many as 95% of adults in the U.S. become infected with EBV at some point in their lives. For those that develop mono, the highest incidence occurs in people between the ages of 15 and 24.

How is it transmitted?

EBV is transmitted through direct contact with virus-infected saliva. Intimate kissing or sharing drinking glasses are the most common routes of transmission. The majority of people with mono are most likely to transmit it just prior to feeling ill. This is called asymptomatic shedding and accounts for the majority of the disease's transmission.

What are the symptoms?

The symptoms of mono may include one or more of the following:

  • Persistent "tired all over" feeling

  • Sore throat and tonsils

  • Swollen lymph glands

  • Fever

  • Headache

  • Enlarged spleen and liver

  • Occasionally, a skin rash or jaundice (yellow tint to the skin)

How long after exposure to EBV will symptoms appear?

If symptoms appear, it typically takes 4 to 6 weeks after being infected. 

How is it diagnosed?

Mono is diagnosed based on the presence of fever, sore throat, and swollen lymph glands. Your medical provider will also request lab tests to confirm the diagnosis. The tests may include a throat culture and blood tests. Be aware that you may need to have symptoms for a week or more before lab tests can identify the virus.

How is it treated?

Because mono is a virus, there are no specific cures or treatments. To help relieve symptoms, you should get plenty of rest, drink plenty of fluids, take an over-the-counter pain reliever such as Tylenol or Advil as needed, and gargle with salt water to relieve a sore throat. Sometimes your provider can give you a stronger prescription pain reliever. Steroids are used in rare cases to decrease swelling of the tonsils. Since the virus can affect the liver, it is also recommended that you abstain from alcohol for 3 months after diagnosis. And because your spleen can become enlarged, it is very important to protect it from rupturing. Strenuous exercise, especially contact sports, must be avoided.

How long will it take to get better?

Recovery may be quicker than you think. Symptoms will ease within 10 days, but don't expect to return to your normal activities for 2 to 3 weeks. 85% of all people with mono are well in 2 weeks and 90% are well in 4 weeks. It is rare for a student to drop out of school because of mono. A few cases of mono are severe enough to interfere with academic work, but these are the exception, not the rule. If you continue to experience symptoms beyond 6 weeks, talk with your medical provider. 

Is it contagious?

Most people have been exposed to the EBV at some point in their life and so are not at risk of developing mono. Because of this, it is not recommended that people with mono isolate themselves from others. Roommates rarely get mono from each other. Avoiding contact with the saliva of an infected person for about 1 month after they had first become ill is recommended.

Can I make an appointment at Health Services?

If you are a Brown student and you are concerned about mononucleosis, you can make a confidential appointment at Health Services by calling 401.863-3953.  Health Services provides a range of services including general health care, inpatient services and emergency medical care. You can request a medical provider by gender or by name. Health Services is located at 450 Brook Street.

Related Links

To learn more about mono, you can visit:

Centers for Disease Control


  • 401.863-2794
    Health Promotion
  • 401.863-3953
    Health Services
  • 401.863-6000
    Sexual Assault Response Line
  • 401.863-4111
  • 401.863-3476
    Counseling & Psychological Services
  • 401.863-4111