Meet the Leaders

  • Director, Principal Investigator of MBoA Training Grant, Professor of Medical Science, Department of Molecular Biology, Cell Biology and Biochemistry

    Cell cycle control, cellular senescence, telomeres, epigenetics

    John Sedivy is recognized for his efforts in mammalian genetics, having developed and pioneered in the late 1980's methods for gene targeting of somatic cells. In 1995 his lab isolated the first viable knockout of c-Myc in a rat fibroblast cell line, which led to his career-long interest in this...

  • Associate Director of the Biology of Aging Initiative, Associate Professor of Molecular Biology, Cell Biology and Biochemistry (Research) Department of Molecular Biology, Cell Biology and Biochemistry

    Computational biology, bioinformatics, gene networks, and chromatin.

    Dr. Kreiling’s research is focused on understanding the connection between age-associated changes in the epigenetic signature of chromatin and the resulting changes in gene expression. Aging is the primary risk factor for the onset of multiple degenerative conditions, such as dementias,...

  • Associate Director for Research, Professor of Biology, Department of Molecular Biology, Cell Biology and Biochemistry

    Genetic control of longevity, calorie restriction, Sir2, resveratrol, Drosophila model system

    Stephen Helfand is recognized for his research on the molecular mechanisms underlying the process of aging, as well as the metabolic changes that occur with and contribute to the deleterious aspects of aging. His group began studying the molecular genetics of aging...

  • Associate Director of MBoA Training Grant, Professor of Biology, Department of Ecology and Evolutionary Biology

    Demography, evolution and genetics of aging, endocrine control of longevity, insulin/IGF signaling, innate immunity, Drosophila model system

    Dr. Tatar is widely recognized for key studies to understand the mechanisms of longevity control through the explicit analysis of age-specific mortality. Trained as an ecologist, Dr. Tatar initially worked on many natural...