The Brown University Ukraine Collaboration is currently undertaking a number of research projects in Ukraine in partnership with local organizations.
1. Controlling Multi-drug Resistant Tuberculosis (MDR-TB) in Ukraine
Collaborators: Bogomolets National Medical University, Kyiv, Ukraine, Dr. Vasyl Petrenko; Ukrianian Institute on Public Health Policy; Boyarka Oblast TB Hospital, Boyarka, Ukraine
This is a mixed-methods study designed to better understand poor treatment outcomes among MDR-TB patients in Ukraine and predictors of those outcomes. Efforts are also being made to build the laboratory capacity at Boyarka hospital to enable DNA extraction from sputum samples, which will eventually allow molecular epidemiology studies.
2. Pediatric TB and MDR-TB in Ukraine
Collaborators: Kyiv City Pediatric TB Hospital in Puscha Vodytsia, Ukraine; HIV Center, Children’s Specialized Hospital OKHMATDIT, Kyiv, Ukraine
Researchers at Brown are collaborating with Ukrainian colleagues to evaluate the state of the TB and MDR-TB epidemics in pediatric patients in Ukraine. Concurrently, this project will assess the lab capacity of Ukraine’s TB hospitals in the interest of incorporating Ukraine into a multi-site research project investigating novel pediatric diagnostic techniques, which is being led by TB researchers at Harvard.
3. Vulnerable Youth in Ukraine
Collaborators: HealthRight International, Director: Halyna Skipalska
This is a mixed-methods project designed to identify risk factors for HIV and other STIs among vulnerable youth and develop interventions to decrease those risks. HealthRight International has been implementing a STEPS program which educates homeless and at-risk youth on topics ranging from basic hygiene and reproductive health to HIV information, violence management and correct condom use. The goal of these efforts is to identify areas that can augment the existing programs and make them more effective.
4. Double stigma as barrier to integrated HIV treatment among HIV infected PWID in Ukraine
Collaboratrs: Karsten Lunze, MD, MPH, DrPH (Boston University); Jeffrey Samet, MD, MA, MPH (Boston University); Timothy Palen Flanigan, MD (Brown University
This project aims to examine the double stigmas of HIV and substance use as a barrier to treatment integration among HIV-infected people who inject drugs (PWID) in Ukraine. This pilot study will leverage the expertise of research groups at Brown University and Boston University and a partner team in Ukraine and will lay the foundation for the development and evaluation of a subsequent stigma intervention.
5. Enhancing Detection of Pediatric Tuberculosis in Ukraine
Collaborators: Bogomolets National Medical University, Kyiv, Ukraine, Dr. Vasyl Petrenko; Kyiv City Pediatric TB Hospital in Puscha Vodytsia, Ukraine; HIV Center, Children's Specialized Hospital OKHMATDIT, Kyiv, Ukraine, Ukrainian Institute on Public Health Policy
This project aims to retrospectively examin autopsy and clinical data of children who have died in Ukraine in an effort to identify all TB-related deaths in children. The second aim of this project is to evaluate the potential for enhancing TB diagnosis in children with a prospective study.
6. Mental Health and HIV/MDR-TB in Ukraine
Collaborators: Robert Paul, PhD (University of Missouri, St. Louis); Timothy Palen Flanigan, MD (Brown University); Omowunmi Aibana, MD, MPH (The University of Texas); Ukrainian Institute on Public Health Policy
This projects aims to provide capacity building for integration of mental health into HIV/MDR-TB treatment in Ukraine. The goal is to improve treatment adherence and patient outcomes among individuals infected with HIV/MDR-TB. The results of this project with help to inform strategies for closing the mental health gap in Ukraine and other regions of the world.