Grant proposals must identify the facilities and resources to be used that are directly applicable to the proposed work. Below please find information on Advance-CTR's facilities and resources. It is encouraged to use this language in grant proposals that involve Advance-CTR. 

Questions? Please contact AdvanceRI@brown.edu

Advance Clinical and Translational Research (Advance-CTR): serves to support and educate clinical and translational researchers in Rhode Island. The goal of Advance-CTR is to enhance collaboration and coordination of translational research in order to accelerate cross-disciplinary discoveries that improve health. Advance-CTR aims to: 1) Foster coordination between translational researchers at our partner institutions, 2) Bring together the diverse clinical research resources to provide a home that facilitates new collaborations, 3) Eliminate obstacles that may prevent researchers from pursuing clinical research initiatives, 4) Educate, mentor and encourage young investigators in clinical research professional development, 5) Facilitate research to gather preliminary data necessary for developing competitive research proposals and 6) Sustain a clinical translational research environment by providing the necessary management and coordination of resources.

Advance-CTR is comprised of an Administrative Core; two Award Cores, the Pilot Projects Program and Professional Development; and three Service Cores, Clinical Research Design, Epidemiology and Biostatistics, Clinical Research Resources and Facilities, and Biomedical Informatics and Cyberinfrastructure Enhancement.

Administrative Core: The Administrative Core serves as the central operations hub for Advance-CTR. It includes two Project Managers, a Communication Manager, and one Assistant who report to the Advance-CTR Administrative Director. These individuals support the PD/PI; Program Coordinator; Strategic Planning Coordinator, the IAC, EAC and Steering Committees; and the six Cores. Administrative Core personnel assist the Core Leads in program management and planning, tracking and evaluation, budget development, allocation of resources, reporting and development of educational initiatives.

Pilot Projects Program: The Pilot Projects Program awards four investigators per year with one-year grants of $75,000 each in direct costs for clinical and translational research. Awarded proposals must be interdisciplinary with a focus on clinical, translational or community research. Priority is given to proposals that address statewide health priorities set forth by the Rhode Island Department of Health. Awardees gain the opportunity to experience planning and preparing research applications in an NIH format, respond to reviews and learn grant management skills in a collaborative, cross-disciplinary environment. Finally, awardees may take advantage of Advance-CTR's research services in both the pre-proposal and post-award stages of their projects.

Professional Development Core: The Professional Development Core provides educational and mentoring opportunities to both junior and senior investigators. The Core includes the Mentored Research Awards program (MRAs), which is geared toward early career-stage investigators, especially those who identify as underrepresented minority individuals in STEM. The MRAs are given annually to three investigators from Brown University and the University of Rhode Island. They are two-year awards that cover 75% salary up to $90,000 in direct costs. An additional $25,000 is also provided to cover research-related expenses or tuition (a Master's degree in Clinical and Translational Research from the Brown University School of Public Health is encouraged). Finally, the awards provide a structured mentoring program and training in clinical and translational research. Awardees are encouraged to take advantage of Advance-CTR's research services in both the pre-proposal and post-award stages of their projects.

Biostatistics Core: The Clinical Research Design, Epidemiology and Biostatistics Core provides a central location for Rhode Island investigators seeking quantitative and qualitative research design and analysis support through Advance-CTR. The Biostatistics Core links investigators with multidisciplinary faculty members and experts in various methodological techniques including biostatistics, epidemiology, qualitative data techniques and measurement and evaluation in health-related research.

Clinical Research Support Core: The Clinical Research Resources and Facilities Core is based at the Lifespan CRC. Clinical Research Support is offered to Rhode Island investigators by highly trained research staff including clinical research coordinators, registered nurses, a medical technologist, and a phlebotomist. Investigators seeking Advance-CTR services have access to regulatory support, subject recruitment, space and support for the conduct for study visits, specimen collection and biobanking.

Biomedical Informatics Core: The Biomedical Informatics and Cyberinfrastructure Enhancement Core employs a team of data scientists to support research endeavors across the full spectrum of biomedicine. The Core offers investigators specific expertise in biological sequence analysis, data capture and management, biomedical data integration, knowledge representation and discovery, natural language processing and decision support.

Dedicated Space: A total of 6,946 square feet is dedicated to Advance-CTR across all partner institutions in Rhode Island. Central offices are located in downtown Providence, Rhode Island, adjacent to the Warren Alpert Medical School of Brown University and less than a mile from the Brown University School of Public Health, Lifespan and Care New England hospital systems. Other partners, including the Providence VA Medical Center and the Rhode Island Quality Institute are less than three miles away from the Administrative Core offices. This includes 2,281 square feet of space for the Administrative Core, the Pilot Project Program and the Biomedical Informatics Core. Shared building-wide resources include a small 209 square foot conference room with capacity of 8 people and a larger 365 square foot conference room with a capacity of 16 people. The building is serviced by a 10 Gigabits per second (Gbps) optical network (Cisco).