850 MHz Bruker Avance III HD
The 850 MHz ASCEND spectrometer is equiped with a cryoprobe and Avance III HD console. The spectrometer is equipped with four full channels and a TCI HCN z-gradient cryoprobe. The instrument is controlled using a Linux workstation running TopSpin 3.2. A room-temperature probe is also available; both probes have automatic tuning and matching capability. We have some photos of the installation, and a video of its being lowered into the facility.
600 MHz Bruker NEO
A Bruker NEO 600 MHz spectrometer was installed in 2018 for solution-state protein NMR experiments. It is equipped with triple-resonance inverse detection cryoprobe with cooled 1H, 13C and 15N preamplifiers. A room temperature probe is also available for this instrument. It is operated using software Topspin 4.0.
500 MHz Bruker Avance IIOur shielded 500 MHz spectrometer generally operates with a TCI HCN z-gradient cryoprobe. The most recent S/N measurement was 4000:1 using the EB 200 method. The Avance III console contains three full-power channels for pulsing on 1H, 13C, and 15N, and a fourth channel with a 20 W amplifier suitable for decoupling 2H. The instrument is controlled using TopSpin 3.1. A room-temperature TXI z-gradient probe is also available if needed; both probes have automatic tuning andmatching capability.