The Darling Lab conducts basic science and translational investigations involving mesenchymal stem cells. Areas of emphasis include single-cell elastic and viscoelastic properties (mechanophenotyping) and cellular biomarker discovery. Ongoing studies are looking at the issue of cellular heterogeneity and its effect on stem cell differentiation and regenerative engineering. Additional work related to these topics and others are pursued through collaborations at Brown University, Rhode Island Hospital, and other research institutions.

Major research tracks in the Darling Lab include:

Single-cell mechanophenotyping Live-cell, gene expression analysis Applying adult stem cell to regenerative engineering Understanding and addressing cellular heterogeneity