Click here: full publication list on pubmed

Brown S, Fawzi NJ, Head-Gordon T. Coarse-grained sequences for protein folding and design. Proc Natl Acad Sci U S A. 100: 10712-10717. (2003).

Fawzi NL, Chubukov V, Clark LA, Brown S, Head-Gordon T. Influence of denatured and intermediate states of folding on protein aggregation. Protein Sci. 14: 993-1003. (2005).

Marianayagam NJ*, Fawzi NL*, Head-Gordon T. Protein folding by distributed computing and the denatured state ensemble. Proc Natl Acad Sci U S A. 102: 16684-16689. (2005). (*equal contributions)

Pfleger BF, Fawzi NJ, Keasling JD. Optimization of DsRed production in Escherichia coli: effect of ribosome binding site sequestration on translation efficiency. Biotechnol Bioeng. 92: 553-558. (2005).

Fawzi NL, Okabe Y, Yap EH, Head-Gordon T. Determining the critical nucleus and mechanism of fibril elongation of the Alzheimer's Abeta(1-40) peptide. J Mol Biol. 365: 535-550. (2007).

Lin MS, Fawzi NL, Head-Gordon T. Hydrophobic potential of mean force as a solvation function for protein structure prediction. Structure. 15: 727-740. (2007).

Yap EH, Fawzi NL, Head-Gordon T. A coarse-grained alpha-carbon protein model with anisotropic hydrogen-bonding. Proteins. 70: 626-638. (2008).

Fawzi NL, Yap EH, Okabe Y, Kohlstedt KL, Brown SP, Head-Gordon T. Contrasting disease and nondisease protein aggregation by molecular simulation. Acc Chem Res. 41: 1037-1047. (2008).

Fawzi NL, Phillips AH, Ruscio JZ, Doucleff M, Wemmer DE, Head-Gordon T. Structure and dynamics of the Abeta(21-30) peptide from the interplay of NMR experiments and molecular simulations. J Am Chem Soc. 130: 6145-6158. (2008).

Fawzi NL, Kohlstedt KL, Okabe Y, Head-Gordon T. Protofibril assemblies of the arctic, Dutch, and Flemish mutants of the Alzheimer's Abeta1-40 peptide. Biophys J. 94: 2007-2016. (2008).

Fawzi NL*, Doucleff M*, Suh JY, Clore GM. Mechanistic details of a protein-protein association pathway revealed by paramagnetic relaxation enhancement titration measurements. Proc Natl Acad Sci U S A. 107: 1379-1384. (2010). (*equal contributions)

Fawzi NL, Ying J, Torchia DA, Clore GM. Kinetics of amyloid beta monomer-to-oligomer exchange by NMR relaxation. J Am Chem Soc. 132: 9948-9951. (2010).

Ruscio JZ, Fawzi NL, Head-Gordon T. How hot? Systematic convergence of the replica exchange method using multiple reservoirs. J Comput Chem. 31: 620-627. (2010).

Ball KA, Phillips AH, Nerenberg PS, Fawzi NL, Wemmer DE, Head-Gordon T. Homogeneous and heterogeneous tertiary structure ensembles of amyloid-beta peptides. Biochemistry. 50: 7612-7628. (2011).

Fawzi NL*, Fleissner MR*, Anthis NJ*, Kalai T, Hideg K, Hubbell WL, Clore GM. A rigid disulfide-linked nitroxide side chain simplifies the quantitative analysis of PRE data. J Biomol NMR. 51: 105-114. (2011). (*equal contributions)

Fawzi NL, Ying J, Ghirlando R, Torchia DA, Clore GM. Atomic-resolution dynamics on the surface of amyloid-beta protofibrils probed by solution NMR. Nature. 480: 268-272. (2011).

Venditti V, Fawzi NL, Clore GM. Automated sequence- and stereo-specific assignment of methyl-labeled proteins by paramagnetic relaxation and methyl-methyl nuclear Overhauser enhancement spectroscopy. J Biomol NMR. 51: 319-328. (2011).

Fawzi NL, Ying J, Torchia DA, Clore GM. Probing exchange kinetics and atomic resolution dynamics in high-molecular-weight complexes using dark-state exchange saturation transfer NMR spectroscopy. Nat Protoc. 7: 1523-1533. (2012).

Venditti V, Fawzi NL, Clore GM. An efficient protocol for incorporation of an unnatural amino acid in perdeuterated recombinant proteins using glucose-based media. J Biomol NMR. 52: 191-195. (2012).

Libich DS*, Fawzi NL*, Ying J, Clore GM. Probing the transient dark state of substrate binding to GroEL by relaxation-based solution NMR. Proc Natl Acad Sci U S A. 110:11361-11366. (2013). (*equal contributions)

Fawzi NL, Libich DS,Ying J, Tugarinov V., Clore GM. Characterizing methyl-bearing side chain contacts and dynamics mediating amyloid β protofibril interactions using 13Cmethyl-DEST and lifetime line broadening. Angew Chem Int Ed Engl. 53:10345-9. (2014) (co-corresponding authors)

Conicella AE, Fawzi NL. The C-terminal threonine of Aβ43 nucleates toxic aggregation via structural and dynamical changes in monomers and protofibrils. Biochemistry. 53:3095-105. (2014)  (corresponding author)

Burke, KA, Janke, AM, Rhine, CL & Fawzi, NL. Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II. Molecular Cell. 60:231-41. (2015) (corresponding author)