Skeletel Muscle and Exercise Intolerance

Exercise intolerance is frequently associated with pulmonary hypertension. Using preclinical models, we are investigating the mechanisms underlying skeletal muscle dysfunction in pulmonary hypertension with particular focus on mitochondrail metabolism.

Recent Publications:

  • McCullough, D. J., Kue, N., Mancini, T., Vang, A., Clements, R. T., & Choudhary, G. (2020). EXPRESS: Endurance Exercise Training in Pulmonary Hypertension increases Skeletal Muscle Electron Transport Chain Supercomplex Assembly. Pulmonary Circulation.