Biology of Aging Research

A typical scene in a mouse fitness center where many different facilities can be enjoyed.A typical scene in a mouse fitness center where many different facilities can be enjoyed.

Members of the Biology of Aging Initiative belong to many academic units throughout Brown and affiliated hospitals.

Our research is directed towards understanding the fundamental mechanisms of aging. Major conceptual areas pursued by our faculty include:

•  genetic pathways of longevity               •  cellular aging                                     
• 
endocrine regulation of longevity     
• 
skeletal aging                                     
• 
epigenetics                                         
• 
genome stability                               
• 
neurodegenerative diseases

We use many experimental model systems, including human cell culture, mice, rabbits, fruit flies and the nematode worm.