Past News

Past News 

Powerful mathematical tools take the guesswork out of highly complex designs 

Super-cavitating hydrofoils are deployed during the take off and they ensure the development of a lift force balancing the weighSuper-cavitating hydrofoils are deployed during the take off and they ensure the development of a lift force balancing the weigh

Researchers from Brown University, led by Professor George Karniadakis, have joined forces with other leading institutions to develop powerful mathematical tools which simplify and reduce the myriad of ambiguities and variables involved in the design of highly complex military vessels. (Read more.)

Best PhD Award in in Biomedical Engineering

Paris Perdikaris received the Best PhD Award in Biomedical Engineering Paris Perdikaris received this award on April 12th at the 5th International Conference on Computational and Mathematical Biomedical Engineering (sponsored by the International Journal for Numerical Methods in Biomedical Engineering). It is awarded every two years to a doctoral thesis that exhibits substantial merit to the field of Biomedical Engineering.

Best Poster:  From Micelles to Cells.  Modeling Mesoscopic Phenomena

 using Particle-Based Models: Theory, Implementation and Applications. Yu-Hang Tang, George Em Karniadakis.  Abstract:  The successful application of computer simulation techniques for solving problems in physical sciences requires interdisciplinary effort spanning theory, software implementation, and application. In this poster, algorithms and strategies are presented for the optimization of two GPU­-accelerated Dissipative Particle Dynamics (DPD) packages that can utilize and push for the limit of thousands of current generation massively parallel processors. It is also presented how to apply petascale DPD simulations to model the separation of rare circulating cancer cells from millions of normal blood cells, as well as the non­equilibrium dynamics of self­assembled structures called vesicles and micelles whose affinity to water changes nonlinearly with respect to system temperature. The presented work demonstrates that a close interplay between computation and science is critical to facilitate the development and adoption of high performance computing for solving practical scientific problems.  

In-Silico Medicine: Multiscale Modeling of Hematological Disorders

Petascale Dissipative Particle Dynamics Simulations of Biomedical Microfluidic Devices

ICFDA’16 Riemann-Liouville award for best paper  

The 2016 International Conference on Fractional Differentiation and its Applications, awarded a recent paper entitled, "Fast solver for fractional di fferential equations based on Hierarchical Matrices," with the distinction of "best paper."  The article was authored by Xuan Zhao, Xiaozhe Hu, Wei Cai and George Em Karniadakis.   Abstract:  A robust and fast solver for the fractional differential equation (FDEs) involving the Riesz fractional derivative is developed using an adaptive fi nite element method on nonuniform meshes. It is based on the utilization of hierarchical matrices (H-Matrices) for the representation of the stiffness matrix resulting from the finite element discretizationof the FDEs. We employ a geometric multigrid method for the solution of the algebraic system of equations. We combine it with an adaptive algorithm based on a posteriori error estimation to deal with general-type singularities arising in the solution of the FDEs.  Through various test examples we demonstrate the efficiency of the method and the high accuracy of the numerical solution even in the presence of singularities. To the best of our knowledge, there are currently no other methods for FDEs that resolve singularities accurately at linear complexity as the one we propose here.  (Read full article.)

How the Spleen Filters Blood

 

Computer model finds slits in the spleen impose a “physical fitness test” on red blood cells.   Pictured on the left is a spleen; on the right are red blood cells. ““We have presented results showing that the spleen is the main organ that defines the shape of the circulating red blood cells” says Ming Dao, a principal research scientist in MIT’s Department of Materials Science and Engineering. Read full story.

Computer Model Demonstrates How Human Spleen Filters Blood

Study provides greater understanding of spleen function and could lead to new treatments for diseases. Read full story.

Research uncovers spleen's role in shaping blood cells

 

Computer models developed at Brown show how red blood cells move through tiny slits in the spleen. The work suggests that the limitations imposed by these slits determine the size of red blood cells. MIT/CMU/Brown.  Read Full Story

A breakthrough for researchers from Brown University, ETH Zurich and the Swiss National Supercomputing Centre (CSCS)

Read blood cells (red) and circulating tumor cells (green) traveling through a microfluidic cell sorting deviceRead blood cells (red) and circulating tumor cells (green) traveling through a microfluidic cell sorting device

Led by Professor George Karniadakis, researchers from Brown UniversityETH Zurich, and the Swiss National Supercomputing Centre (CSCS), join forces to fight against tumor formation and sickle cell anemia, using a mathematical understanding of biological systems to conquer hematologically based diseases.Read full story.

Other News Features