Publications

Genetics
     Books and Book Chapters

Derek Aguiar, Eric Morrow, and Sorin Istrail. .Tractatus: An Exact and Subquadratic Algorithm for Inferring Identical-by-Descent Multi-shared Haplotype Tracts. In: Roded Sharan, ed. Research in Computational Molecular Biology. Springer International Publishing. Lecture Notes in Computer Science Vol. 8394, 2014, 1-17.

Eric M. Morrow and Christopher A. Walsh. Isolate Populations and Rare Variation in Autism Spectrum Disorders. In: David Amaral, Daniel Geschwind, and Geraldine Dawson, eds. Autism Spectrum Disorders. Oxford: Oxford University Press. 2011, 766-775.

     Journal Articles and Reviews
Morrow EM. MicroRNAs in Copy Number Variants in Schizophrenia: Misregulation of Genome-wide Gene Expression Programs. Biological Psychiatry. 2015; 77 (2) : 93-4.

Howe YJ, Yatchmink Y, Viscidi EW, Morrow EM. Ascertainment and gender in autism spectrum disorders. Journal of the American Academy of Child & Adolescent Psychiatry. 2014; 53 (6) : 698-700.

McLean RL, Johnson Harrison A, Zimak E, Joseph RM, Morrow EM. Executive function in probands with autism with average IQ and their unaffected first-degree relatives. Journal of the American Academy of Child & Adolescent Psychiatry. 2014; 53 (9) : 1001-9.

Pescosolido MF, Schwede M, Johnson Harrison A, Schmidt M, Gamsiz ED, Chen WS, Donahue JP, Shur N, Jerskey BA, Phornphutkul C, Morrow EM. Expansion of the clinical phenotype associated with mutations in activity-dependent neuroprotective protein. Journal of Medical Genetics. 2014; 51 (9) : 587-9.

Schwede M, Garbett K, Mirnics K, Geschwind DH, Morrow EM. Genes for endosomal NHE6 and NHE9 are misregulated in autism brains. Molecular Psychiatry. 2014; 19 (3) : 277-9.

Pescosolido, M.F., Stein, D.M., Schmidt, M., El Achkar, C.M., Sabbagh, M., Rogg, J.M., Tantravahi, U., McLean, R.L., Liu, J.S., Poduri, A., and Morrow, E.M. (2014). Genetic and phenotypic diversity of NHE6 mutations in Christianson syndrome. Ann Neurol 76: 581-593 (PMID: 25044251).

Pescosolido, M.F., Schwede, M., Johnson Harrison, A., Schmidt, M., Gamsiz, E.D., Chen, W.S., Donahue, J.P., Shur, N., Jerskey, B.A., Phornphutkul, C., and Morrow, E.M. (2014). Expansion of the clinical phenotype associated with mutations in Activity-Dependent Neuroprotective Protein. J Med Genet 51: 587-589 (PMID: 25057125; PMCID: PMC4135390).

Gerber, A., Morrow, E.M., Sheinkopf, S.J., and Anders, T. (2014). The Rhode Island Consortium for Autism Research and Treatment (RI-CART): A new statewide autism collaborative. RI Med J 97: 31-34 (PMID: 24791265; PMCID: PMC4134665).

Stein, D.M., Gerber, A.H., and Morrow, E.M. (2014). Inaugural Christianson Syndrome Association conference: families meeting for the first time. J Neurodev Disord 6: 13 (PMID: 25273398; PMCID: PMC4038054).

Chaste, P., Sanders, S.J., Mohan, K.N., Klei, L., Song, Y., Murtha, M.T., Hus, V., Lowe, J.K., Willsey, A.J., Moreno-De-Luca, D., Yu, T.W., Fombonne, E., Geschwind, D., Grice, D.E., Ledbetter, D.H., Lord, C., Mane, S.M., Martin, D.M., Morrow, E.M., Walsh, C.A., Sutcliffe, J.S., State, M.W., Martin, C.L., Devlin, B., Beaudet, A.L., Cook, E.H. Jr., and Kim, S.-J. (2014). Modest impact of risk for autism spectrum disorder of rare copy number variants at 15q11.2, specifically breakpoints 1 to 2. Autism Res 7: 355-362 (PMID: 24821083).

Yeo, R.A., Gangestad, S.W., Walton, E., Ehrlich, S., Pommy, J., Turner, J.A., Liu, J., Mayer, A.R., Schulz, S.C., Ho, B.C., Bustillo, J.R., Wassink, T.H., Sponheim, S.R., Morrow, E.M., and Calhoun, V.D. (2014). Genetic influences on cognitive endophenotypes in schizophrenia. Schizophr Res 156: 71-75 (PMID: 24768440).

Abrahams, B.S.*, Arking, D.E.*, Campbell, D.B.*, Mefford, H.C.*, Morrow, E.M.*, Weiss, L.A.*, Menashe, I., Wadkins, T., Banerjee-Basu, S., and Packer, A. (2013). SFARI Gene 2.0: A community-driven knowledgebase for the autism spectrum disorders (ASDs). Mol Autism 4: 36 (PMID: 24090431; PMCID: PMC3851189). *Authors contributed equally and are listed alphabetically

Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee, S.H., Ripke, S., Neale, B.M., Faraone, S.V., Purcell, S.M., Perlis, R.H., Mowry, B.J., Thapar, A., .[210 authors alphabetically listed], Morrow, E.M., Moskvina, V., .[125 authors alphabetically listed], Yu, T.W., Zammit, S., Zandi, P.P., Zhang, P., Zitman, F.G., Z�llner, S.; International Inflammatory Bowel Disease Genetics Consortium (IIBDGC), Devlin, B., Kelsoe, J.R., Sklar, P., Daly, M.J., O.Donovan, M.C., Craddock, N., Sullivan, P.F., Smoller, J.W., Kendler, K.S., and Wray, N.R. (2013). Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet 45: 984-994 (PMID: 23933821; PMCID: PMC3800159).

Gamsiz, E.D., Viscidi, E.W., Frederick, A.M., Nagpal, S., Sanders, S.J., Murtha, M.T., Simons Simplex Collection Genetics Consortium, Triche, E.W., Geschwind, D.H., State, M.W., Istrail, S., Cook, E.H. Jr., Devlin, B., and Morrow, E.M. (2013). Intellectual disability is associated with increased runs-of-homozygosity in simplex autism. Am J Hum Genet 93: 103-109 (PMID: 2380515; PMCID: PMC3710760).

Pescosolido, M.F., Gamsiz, E.D., Nagpal, S., and Morrow, E.M. (2013). Distribution of disease-associated copy number variants across distinct disorders of cognitive development. J Am Acad Child Adolesc Psychiatry 52: 414-430 (PMID: 23582872; PMCID: PMC3774163).

Minhas, H.M., Pescosolido, M.F., Schwede, M., Piasecka, J., Gaitanis, J., Tantravahi, U., and Morrow E.M. (2013). An unbalanced translocation involving loss of 10q26.2 and gain of 11q25 in a pedigree with autism and cerebellar juvenile pilocytic astrocytoma. Am J Med Genet Part A 161: 787-791 (PMID: 23495067; PMCID: PMC3606653).

Yeo, R.A., Gangestad, S.W., Liu, J., Ehrlich, S., Thoma, R.J., Pommy, J., Mayer, A.R., Schulz, S.C., Wassink, T.H., Morrow, E.M., Bustillo, J.R., Sponheim, S.R., Ho, B.C., and Calhoun, V.D. (2013). The impact of copy number deletions on general cognitive ability and ventricle size in patients with schizophrenia and healthy controls. Biol Psychiatry 73: 540-545 (PMID: 23237311; PMCID: PMC3582736).

Yu, T.W., Chahrour, M.H., Coulter, M.E., Jiralerspong, S., Okamura-Ikeda, K., Ataman, B., Schmitz-Abe, K., Harmin, D.A., Adli, M., Malik, A.N., D.Gama, A.M., Lim, E.T., Sanders, S.J., Mochida, G.H., Partlow, J.N., Sunu, C.M., Felie, J.M., Rodriguez, J., Nasir, R.H., Ware, J., Joseph, R.M., Hill, R.S., Kwan, B.Y., Al-Saffar, M., Mukaddes, N.M., Hashmi, A., Balkhy, S., Gascon, G.G., Hisama, F.M., LeClair, E., Poduri, A., Oner, O., Al-Saad, S., Al-Awadi, S.A., Bastaki, L., Ben-Omran, T., Teebi, A.S., Al-Gazali, L., Eapen, V., Stevens, C.R., Rappaport, L., Gabriel, S.B., Markianos, K., State, M.W., Greenberg, M.E., Taniguchi, H., Braverman, N.E., Morrow. E.M., and Walsh, C.A. (2013). Using whole-exome sequencing to identify inherited causes of autism. Neuron 77: 259-273 (PMID: 23352163; PMCID: PMC3694430). [cover photo]

Klei, L., Sanders, S.J., Murtha, M.T., Hus, V., Lowe, J.K., Willsey, A.J., Moreno-De-Luca, D., Yu, T.W., Fombonne, E., Geschwind, D., Grice, D.E., Ledbetter, D.H., Lord, C., Mane, S.M., Martin, C.L., Martin, D.M., Morrow, E.M., Walsh, C.A., Melhem, N.M., Chaste, P., Sutcliffe, J.S., State, M.W., Cook, E.H. Jr., Roeder, K., and Devlin, B. (2012). Common genetic variants, acting additively, are a major source of risk for autism. Mol Autism 3: 9 (PMID: 23067556; PMCID: PMC3579743).

Pescosolido, M.F., Yang, U., Sabbagh, M., and Morrow, E.M. (2012). Lighting a path: Genetic studies pinpoint neurodevelopmental mechanisms in autism and related disorders. Dialogues Clin Neurosci 14: 239-252 (PMID: 23226950; PMCID: PMC3513679).

Aguiar, D., Halldorsson, B.V., Morrow, E.M., and Istrail, S. (2012). DELISHUS: An Efficient and exact algorithm for genome-wide detection of hemizygous deletion polymorphism in autism. Bioinformatics 28: i154-i162 (PMID: 22689755; PMCID: PMC3371866).

Mefford, H.C., Rosenfeld, J.A., Shur, N., Slavotinek, A.M., Cox, V.A., Hennekam, R., Firth, H.V., Willatt, L., Wheeler, P., Morrow, E.M., Cook, J., Sullivan, R., Oh, A., Zonana, J., Keller, K., Hannibal, M.C., Ball, S., Kussmann, J., Gorski, J., Zelewski, S., Banks, V., Smith, W., Smith, R., Paull, L., Rosenbaum, K.N., Amor, D.J., Silva, J., Lamb, A., and Eichler, E.E. (2012). Further clinical and molecular delineation of the 15q24 microdeletion syndrome: Fifteen newly reported patients and two atypical deletions. J Med Genet 49: 110-118 (PMID: 22180641; PMCID: PMC3261729).

Sofos, E., Pescosolido, M.F., Quintos, J.B., Abuelo, D., Gunn, S., Hovanes, K., Morrow, E.M., and Shur, N. (2012). A novel familial 11p15.4 microduplication associated with intellectual disability, dysmorphic features, and obesity with involvement of the ZNF214 gene. Am J Med Genet 158A(1): 50-58 (PMID: 22052655).

Sanders, S.J., Ercan-Sencicek, A.G., Hus, V., Luo, R., Murtha, M., Moreno-De-Luca, D., Chu, S.H., Moreau, M., Gupta, A., .[49 authors], Morrow, E.M., Ledbetter, D.H., Fombonne, E., Lord, C., Martin, C.L., Brooks, A.I., Sutcliffe, J., Cook, E.H. Jr., Geschwind, D., Roeder, K., Devlin, B., and State, M.W. (2011). Multiple recurrent de novo copy number variations (CNVs), including duplications of the 7q11.23 Williams-Beuren syndrome region are strongly associated with autism. Neuron 70: 863-885 (PMID: 21658581; PMCID: PMC3939065).

Morrow, E.M. (2010). Genomic copy number variation in disorders of cognitive development. J Am Acad Child Adolesc Psychiatry 49: 1091-1104 (PMID: 20970697; PMCID: PMC3137887).

Ching, M.S., Shen, Y., Tan, W.H., Jeste, S.S., Morrow, E.M., Mukaddes, N.M., Yoo, S.Y., Hanson, E., Hundley, R., Austin, C., Becker, R.E., Berry, G.T., Driscoll, K., Engle, E.C., Friedman, S., Gusella, J.F., Hisama, F.M., Irons, M.B., Lafiosca, T., LeClair, E., Miller, D.T., Neessen, M., Picker, J.D., Rappaport, L., Rooney, C.M., Sarco, D.P., Stoler, J.M., Walsh, C.A., Wolff, R.R., Zhang, T., Nasir, R., and Wu, B.L. (2010). Deletions of NRXN1 (neurexin-1) predispose to a wide spectrum of developmental disorders. Am J Med Genet B: Neuropsychiatr Genet 153: 937-947 (PMID: 20468056; PMCID: PMC3001124).

Ehrlich, S., Morrow, E.M., Roffman, J.L., Wallace, S.R., Naylor, M., Bockholt, H.J., Lundquist, A., Yendiki, A., Ho, B., White, T., Manoach, D.S., Clark, V.P., Calhoun, V.D., Gollub, R.L., and Holt, D.J. (2010). The COMT Val108/158Met polymorphism and medial temporal lobe volumetry in patients with schizophrenia and healthy adults. Neuroimage 53: 992-1000 (PMID: 20026221; PMCID: PMC2888809).

Weiss, L.A., Arking, D.E., Gene Discovery Project of Johns Hopkins and the Autism Consortium, .[16 authors], Korn, J., Kuruvilla, F., McCarroll, S., Morrow, E.M., Neale, B., Purcell, S., .[170 authors], Daly, M.J., and Chakravarti, A. (2009). A genome-wide linkage and association scan reveals novel loci for autism. Nature 461: 802-808 (PMID: 19812673; PMCID: PMC2772655).

Morrow, E.M., Yoo, S.Y., Flavell, S.W., Kim, T.K., Lin, Y., Hill, R.S., Mukaddes, N.M., Balkhy, S., Gascon, G., Hashmi, A., Al-Saad, S., Ware, J., Joseph, R.M., Greenblatt, R., Gleason, D., Ertelt, J.A., Apse, K.A., Bodell, A., Partlow, J.N., Barry, B., Yao, H., Markianos, K., Ferland, R.J., Greenberg, M.E., and Walsh, C.A. (2008). Identifying autism loci and genes by tracing recent shared ancestry. Science 321: 218-223 (PMID: 18621663; PMCID: PMC2586171). [cover photo]


Clinical Phenotype and Neuropsychiatry
     Books and Book Chapters

Eric M. Morrow, Joshua L. Roffman, Daniel H. Wolf, and Joseph T. Coyle. .Psychiatric Neuroscience:� Incorporating Pathophysiology into Clinical Case Formulation. In: Theodore A. Stern, Jerrold F. Rosenbaum, Maurizio Fava, Joseph Biederman, and Scott Rauch, eds. Massachusetts General Hospital: Comprehensive Clinical Psychiatry. Philadelphia: Mosby/Elsevier. 2008, 543-564. [cover photo]

Eric M. Morrow.� .The boy that is happiest when left alone. In: Sandra I. Kim, Todd A. Swanson, and Jonathan D. Wasserman, eds. Underground Clinical Vignettes: Pediatrics 4th ed. Lippincott Williams & Wilkins, 2007.

Journal Articles and Reviews

Harrison, A.J., Zimak, E.H., Sheinkopf, S.J., Manji, K.P., and Morrow, E.M. (2014). Observation-centered approach to ASD assessment in Tanzania. Intellect Dev Disabil 52: 330-347 (PMID: 25247726).

McLean, R.L., Johnson Harrison, A., Zimak, E., Joseph, R.M., and Morrow, E.M. (2014). Executive function in probands with autism with average IQ and their unaffected first-degree relatives. J Am Acad Child Adolesc Psychiatry 53: 1001-1009 (PMID: 25151423; PMCID: PMC4144046).

Howe, Y.J., Yatchmink, Y., Viscidi, E.W., and Morrow, E.M. (2014). Ascertainment and gender in autism spectrum disorders. J Am Acad Child Adolesc Psychiatry 53: 698-700 (PMID: 24839890).

Viscidi, E.W., Spence, S.J., Buka, S.L., Morrow, E.M., and Triche, E.W. (2014). The association between epilepsy and autism symptoms and maladaptive behaviors in children with autism spectrum disorder. Autism 18: 996-1006. Published online October 28, 2013; doi: http://dx.doi.org/10.1177/1362361313508027 (PMID: 24165273; PMCID: PMC4002664).

Viscidi, E.W., Triche, E.W., Pescosolido, M.F., McLean, R.L., Joseph, R.M., Spence, S.J., and Morrow, E.M. (2013). Clinical characteristics of children with autism spectrum disorder and co-occurring epilepsy. PLoS One 8: e67797 (PMID: 23861807; PMCID: PMC3701630).

Chaste, P., Klei, L., Sanders, S.J., Murtha, M.T., Hus, V., Lowe, J.K., Willsey, A.J., Moreno-De-Luca, D., Yu, T.W., Fombonne, E., Geschwind, D., Grice, D.E., Ledbetter, D.H., Lord, C., Mane, S.M., Lese Martin, C., Martin, D.M., Morrow, E.M., Walsh, C.A., Sutcliffe, J.S., State, M.W., Devlin, B., Cook, E.H. Jr., and Kim, S.-J. (2013). Adjusting head circumference for covariates in autism: Clinical correlates of a highly heritable continuous trait. Biol Psychiatry 74: 576-584 (PMID: 23746936; PMCID: PMC3772969).

Cellular Mechanisms
     Books and Book Chapters

Eric M. Morrow.� .Neuronal Physiology and the Autonomic Nervous System. In: Drs. Seifter, Ratner, and Sloane, eds. Concepts in Medical Physiology. Lippincott Williams & Wilkins.� October 2005.

     Journal Articles and Reviews

Ouyang, Q., Lizarraga, S.B., Schmidt, M., Yang, U., Gong, J., Ellisor, D., Kauer, J.A., and Morrow, E.M. (2013). Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development. Neuron 80: 97-112 (PMID: 24035762; PMCID: PMC3830955). [cover photo; highlighted by commentary in same issue; chosen as an Editors. Choice at Science Signaling]

Schwede, M., Garbett, K., Mirnics, K., Geschwind, D.H., and Morrow, E.M. (2014). Genes for endosomal NHE6 and NHE9 are misregulated in autism brains. Mol Psychiatry 19: 277-279. Published online March 19, 2013; doi: http://dx.doi.org/10.1038/mp.2013.28 (PMID: 23508127; PMCID: PMC3932404).

Lizarraga, S.B., Coser, K.R., Sabbagh, M., and Morrow, E.M. (2012). Methods for study of neuronal morphogenesis: Ex vivo RNAi electroporation in embryonic murine cerebral cortex. J Vis Exp 63: 3621 (PMID: 22643694; PMCID: PMC3369626).

Gamsiz, E.D., Ouyang, Q., Schmidt, M., Nagpal, S. and Morrow, E.M. (2012). Genome-wide transcriptome analysis in murine neural retina using high-throughput RNA sequencing. Genomics 99: 44-51 (PMID: 22032952; PMCID: PMC3392719).

Walsh, C.A., Morrow, E.M., and Rubenstein, J.L. (2008). Autism and brain development. Cell 135: 396-400 (PMID: 18984148; PMCID: PMC2701104).