Eosinophilic granuloma

 

These non-neoplastic tumors may be confined to the lung or be part of a systemic disease such as histiocytosis X or Letterer-Siwe disease. There is an extensive histiocytic infiltrate and a xanthomatous (Gk. xanthos – yellow) appearance. Often there are other inflammatory cells including lymphocytes, plasma cells, and, as in this case, eosinophils. Giant cells may be present (not illustrated).

 

1 minute clinical correlation

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