Daniel Michael Weinreich
Assistant Professor of Biology
Ecology and Evolutionary Biology and Center for Computational Molecular Biology
Ph.D., Harvard University

I am interested in Darwinian evolution at the level of individual mutations within protein coding genes. This problem is made more complicated and interesting by the fact of epistasis: mutational effects on phenotype often vary dramatically with genetic background. Theoretically I am interested in defining tools to describe epistasis and its influence on natural selection mediated by mutation and recombination. Experimentally I am interested in characterizing the patterns of epistasis, particularly in mutations responsible for drug resistance of pathogenic microbes.

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