Basaloid carcinoma

These low and high magnification photos of the tumor show nests of basaloid cells with peripheral palisading.  The cells of basaloid carcinoma are positive for cytokeratin and negative for neuroendocrine markers. In some tumors basaloid pattern is mixed with patterns consistent with adenocarcinoma, large cell carcinoma, or squamous cell carcinoma. The World Health Organization classifies basaloid carcioma under large cell carcinomas.

This tumor carries a poor prognosis; a 15% 5 year survival rate in one study. Basaloid tumors can occur in the skin, anal canal, or in the upper or lower respiratory tract.