Current Projects

In Silico Identification of Phytotherapies [Sarkar]

Plants have been acknowledged as forming the basis of medicines dating back to the most ancient civilizations. To complement synthetic drug discovery processes, there remains a significant opportunity for identifying potential new therapies from plant-based sources ("phyto-therapies"). The overall goal of this NIH-funded project, which is being done in partnership with the New York Botanical Garden (Co-PI Dr. Wayne Law), is to develop a semantically integrated framework that could be used to identify and validate potential phytotherapies embedded within ethnobotanical and biomedical knowledge sources, and thus encourage the conservation of this knowledge and biodiversity.

Leveraging the EHR to Collect and Analyze Social, Behavioral & Familial Factors [Chen]

The importance of understanding interactions among social, behavioral, environmental, and genetic factors and their relationship to health has led to greater interest in studying these determinants of disease in the biomedical research community. The overall goal of this NIH-funded project, which is being done in partnership with the University of Minnesota and University of Vermont, is to use electronic health record (EHR) data and computational techniques to study these interactions for conditions such as pediatric asthma and adult epilepsy.