Kittichai Promrat, MD

Associate Professor of Medicine

Director of Gastroenterology

Providence VA Medical Center

phone: 401-273-7100 ext 3456

E-mail:[email protected]

Research and Clinical Interests:

My primary research interests include nonalcoholic fatty liver disease (NAFLD) and viral hepatitis.  I am interested in developing new therapeutic approaches based on disease pathogenesis.  I have investigated how weight loss through lifestyle modifications affects lifer histology and metabolic environment in patients with NASH.   More recent efforts have focused on novel interventions in NASH (such as manipulation of gut microbiome through fecal microbiota transplantation, etc.).  Another area of interest is in HCV care delivery focusing on improving various steps in the HCV care cascade.

Selected Publications:

Lee P, Promrat K, Mallette C, Flynn M, Beutler E. A juvenile hemochromatosis patient homozygous for a novel deletion of cDNA nucleotide 81 of hemojuvelin. Acta Haematol. 2006;115(1-2):123-7.

Promrat K, Wands JR.  Aetiology of fulminant hepatitis.  In:  Viral Hepatitis, 3rd Edition.  Thomas H, Zuckerman A, Lemon S (eds).  England:Blackwell Publishing 2005;651-65.

Promrat K, Lutchman G, Uwaifo GI, Freedman RJ, Soza A, Heller T, Doo E, Ghany M, Premkumar A, Park Y, Liang TJ, Yanovski JA, Kleiner DE, Hoofnagle JH. A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology. 2004 Jan; 39(1): 188-96.

Promrat K, Liang TJ. Chemokine systems and hepatitis C virus infection: is truth in the genes of the beholders? Hepatology. 2003 Dec;38(6):1359-62.

Hoofnagle JH, Ghany MG, Kleiner DE, Doo E, Heller T, Promrat K, Ong J, Khokhar F, Soza A, Herion D, Park Y, Everhart JE, Liang TJ. Maintenance therapy with ribavirin in patients with chronic hepatitis C who fail to respond to combination therapy with interferon alfa and ribavirin. Hepatology. 2003 Jul;38(1):66-74.

Promrat K, McDermott DH, Gonzalez CM, Kleiner DE, Koziol DE, Lessie M, Merrell M, Soza A, Heller T, Ghany M, Park Y, Alter HJ, Hoofnagle JH, Murphy PM, Liang TJ. Associations of chemokine system polymorphisms with clinical outcomes and treatment responses of chronic hepatitis C. Gastroenterology. 2003 Feb;124(2):352-60. Erratum in: Gastroenterology. 2003 Apr;124(4):1168.