Research Funding

The Center to Advance Predictive Biology is supported by the NSF EPSCoR Rhode Island Consortium for Coastal Ecology Assessment, Innovation, and Modeling' (RI C-AIM).  




Current center-associated research funding

Kim Boekelheide (PI),  NIH U01 ES028184:  Brown University Bioengineering Research Partnership (BRP), "Human 3D microtissues for toxicity testing via integrated imaging, molecular and functional analyses".  $2,562,311 total costs, 9/15/2017 - 7/31/2022.

Geoffrey Bothun (PI), Breea Govenar (Co-PI), Neal Overstrom (Co-PI), Lewis Rothstein (Co-PI), Jeffrey Morgan (Co-PI), NSF EPSCoR 1655221: "RII Track-1: Rhode Island Consortium for Coastal Ecology Assessment, Innovation, and Modeling (C-AIM)". $ 19 million total costs,  9/01/2017 - 8/31/2022.

Eric Darling (PI), Seed Award, Brown University: "Probing the role of mechanical forces in tissue assembly using in situ force sensors". 01/01/2019-06/30/2020.

Prior research funding

Robbert Creton (PI), NIH / Office of the Director, S10 OD023461: "SEM for serial block-face imaging".  $790,587 total costs,  04/15/2017 – 04/14/2018.

Kim Boekelheide (PI) 5 TR01 ES020750 (Hartung, PI): “Mapping the Human Toxome by Systems Toxicology,” $120,583 annual direct costs, 09/01/11-06/30/16, subcontract from the Johns Hopkins School of Public Health.

Robert Hurt (PI), Huajian Gao (Co-PI), and Agnes Kane (Co-PI), NSF CBET 1344097: “INSPIRE TRACK 1: Computational Design for the Safe Development of High Aspect Ratio Nanomaterials,” $799,999 total costs, 11/01/13-10/31/16.

Ulrike Mende (PI), Choi (Co-I), NIH/NHLBI R21 HL113918, “Advancing Experimental Models to Study Intercellular Communication of Cardiac Cells”, $275,000 total direct cost, 01/16/13 -12/31/15.

Ulrike Mende (PI), Choi (Co-I), NIH/NHLBI R01 HL114784, “Regulation of Gq Signaling in Cardiac Fibroblasts and its Role in Cardiac Remodeling”, $303,031 annual direct cost, 09/01/13 - 05/31/18.    

Bum-Rak Choi (Co-PI), Kareen Coulombe (Co-PI), Ulrike Mende (Co-PI). Brown University DEANS Award, "Functional Integration of Aligned Engineered Cardiac Tissue in Infarcted Heart", $80,000 total direct costs, 07/01/14 - 12/31/15.

Jeff Morgan (PI) NSF Major Research Instrument: “Development of a Bio-Pick and Place Instrument for the Fabrication of 3D Organs from Complex Shaped Living Building Parts” $1,397,150 total costs, 09/01/14 - 08/31/17.

Kim Boekelheide, Jeffrey Morgan, Robert Hurt, and Agnes Kane, Unilever, “Development and Validation of a Unique In Vitro Predictive Biology Platform for Toxicity Testing,” $85,000 total costs, 11/26/14-11/25/15.

Ian Wong (PI), Agnes Kane (Co-PI), and Robert Hurt (Co-PI), 2015 Brown Seed Award, "Engineering Cell Morphology and Phenotype using Bioinspired Graphene Nanoarchitectures," $60,000 total costs, 4/1/15-6/30/16.

Ian Wong (PI), Rhode Island Foundation Medical Research Grant. “Targeting the Epithelial-Mesenchymal Transition using 3D Tumor Spheroids.” $15,000 total costs. 06/01/15-08/31-16.