The Rodent Behavioral Phenotyping Core (RBPC) occupies a 1083 sq ft workroom. The core is overseen by the Carney Institute for Brain Science and directed by Dr. Arturo Andrade, who has more than 10 years of experience in rodent behavioral testing. The RBPC is subdivided into 5 interconnected testing rooms, each room houses an independent workstation. Each workstation is equipped with ANY-MAZE or Ethovison XT tracking software, high-definition digital video cameras, and computers for data analysis. The core is in the same building of the Animal Care Facility (ACF) to allow ready access from housing rooms. We offer a wide variety of behavioral assays outlined below: Locomotor activity (Open Field and Chronic home-cage monitoring), Anxiety-like behavior (Elevated-Zero Maze, Open field, Novelty-Induced Hypophagia, Novelty-Suppressed Feeding, and Light/Dark Box), Learning & Memory (Contextual and Cued Fear conditioning, Extinction Learning, Morris Water Maze, Novel Object Location, Novel Object Recognition, Y-Maze, Barnes Maze, and Radial Maze), Depressive-like behavior (Forced Swim, Learned Helplessness, Social Defeat, Restrain Stress, Variable Foot Shock, Tail Suspension, Sucrose Preference), Homecage Behaviors (Grooming, Feeding, Drinking, Locomotion, Climbing, and Rearing), Social Behavior (Social Novelty, Social Interaction, Resident Intruder, Social Place Preference), Olfactory Function (Olfactory Cross-habituation and Olfactory Generalization), Sensory Function (Hotplate, Shock Threshold, Automated Von Fray Filaments for mechanical testing, thermal plantar testing or Hargreaves test), Motor Function (Accelerating Rotarod, wire-hang test, Grip Strength, and Gait Analysis). However, the RBPC also offers the capability to adapt our equipment to the research needs of PIs.