Dr. Doug Erwin
Curator of Paleozoic Invertebrates
Smithsonian Institution, National Museum of Natural History
Evolutionary Dynamics of Gene Regulation
The evolution of gene regulation can be considered from the perspective of a developmental biologist, interested in how regulatory mechanisms and patterns change, and how these changes facilitate evolution of the phenotype. They can also be considered from the standpoint of the evolutionary biologist, interested in the developmental underpinnings of evolutionary patterns. I will outline the nature of changes in gene regulation at three different levels: 1) the assembly of metazoan regulatory mechanisms during the early history of animals; 2) changes associated with macroevolutionary events such as evolutionary innovations; and 3) changes in gene regulatory networks associated with microevolutionary events such as speciation and adaptive radiations.
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