The Cancer Biology Program brings together basic and translational investigators with expertise in mechanisms of cancer development, cell signaling, DNA repair, aging, stem cells, genomics, and tumor heterogeneity. Program meetings are held every two weeks throughout the year. Several program members have expertise in toxicology including activity of heavy metals and toxic waste that may impact on cancer rates in Rhode Island. The group is interdisciplinary and includes members from several basic and clinical departments with laboratories at Brown University, Lifespan and their affiliated hospitals.

The goal of program meetings is to bring members together to foster collaborative research in basic and translational cancer biology while taking advantage of advanced technologies and capabilities provided as services through core facilities. Efforts to translate novel concepts are supported by the Translational Research Disease Groups (TRDGs) which are additional cancer disease-based group meetings that occur in parallel to the Cancer Biology Program Meetings. Each of the 11 disease-based TRDGs meets every 2-3 months, with emerging projects being presented at the Cancer Biology Program meetings.

  • John Sedivy
    John Sedivy, PhD

    Aging and cancer, Effectors of senescent states, Biology of Aging, Cancer Signaling Networks

  • Anatoly Zhitkovitch
    Anatoly Zhitkovitch, PhD

    DNA repair and cancer, Formaldehyde Genotoxicity, Genotoxicity of Chromium Compounds

Group Members

Joseph M Braun, PhD

Associate Professor of Epidemiology

Laurent Brossay, PhD

Charles A. and Helen B. Stuart Professor of Medical Science, Chair of Molecular Microbiology and Immunology, Professor of Molecular Microbiology and Immunology

Elizabeth O Harrington, PhD

Associate Dean for Graduate and Postdoctoral Studies in the Division of Biology and Medicine, Professor of Medicine

Robert Hurt, PhD

Professor of Engineering

Blanche C Ip, PhD

Assistant Professor of Molecular Pharmacology, Physiology and Biotechnology (Research

Nicola Neretti, PhD

Associate Professor of Molecular Biology, Cell Biolgy, and Biochemistry

Elena Oancea, PhD

Associate Professor of Medical Science

Arthur R Salomon, PhD

Associate Professor of Biology, Associate Professor of Chemistry

Shuping Tong, MD, PhD

Associate Professor of Medicine, Division of Gastroenterology Brown University

Wentian Yang, MD, PhD

Associate Professor of Orthopaedics, Associate Professor of Medicine

Lalit Buera, PhD

Assistant Professor of Molecular Microbiology and Immunology

Ali Amin
Ali Amin, MD

TRDG Member (GU Cancer); GU Pathology

Douglas Anthony
Douglas Anthony, MD, PhD

TRDG Leader, (CNS Cancer); Neuropathology, GBM, Epigenetics

Jeffrey A. Bailey, MD, PhD

Associate Professor of Pathology and Laboratory Medicine, Burkitt’s Lymphoma, Computational Biology, Genetics

Thomas Bartnikas
Thomas Bartnikas, MD, PhD

Heavy metals toxicology

Peter Belenky, PhD

Assistant Professor of Molecular Microbiology and Immunology

Paul Bertone, PhD

Core Director (Single Cell Technologies); TRDG Member, Bioinfomatics Single cell profiling

Kim Boekelheide, MD, PhD

Professor of Medical Science, Director of Superfund Research

Wayne Bowen
Wayne Bowen, PhD

Sigma 2 receptor in cancer, Glycolytic hallmarks, Ceramide

Alexander Brodsky
Alexander Brodsky, PhD

Cancer metabolism, Tumor stroma, Immune biomarkers

Mariana Canepa
Mariana Canepa, MD

Cytopathology, Breast cancer, Her2 Thyroid cancer

Weibiao Cao
Weibiao Cao, MD, PhD

GI Pathology, TGR5 Barrett’s; esoph ca

Michelle Dawson
Michelle Dawson, PhD

Quantitative biophysical analysis, Cell-matrix interactions, Tumor heterogeneity

Suzanne De La Monte, MD, MPH

Insulin, IGF signaling, Neuronal cell death, Neuropathology

Alexandra Deaconescu
Alexandra M Deaconescu, PhD

Transcription-coupled DNA repair, Cytoskeleton regulation

Xiaoqun Dong, PhD

Oncofetal protein, tumor development and progression in various types of cancer

Patrycja Dubielecka-Szczerba
Patrycja Dubielecka-Szczerba, PhD

TRDG Co-Leader (Hematological Malignancies). Core Director (CyTOF); Stem cell biology, Abl kinase, Bone marrow microenvironment.

Christopher Elco, MD, PhD

Cutaneous lymphomas, Hematopathology, TLRs, Melanoma

Jack Elias
Jack Elias, MD

Lung cancer, Chitinase-like targets, Immune mechanisms

William Fairbrother
William Fairbrother, PhD

RNA genomics, Disease mutation, Precision medicine

Nicolas Lux Fawzi, PhD

The structure, dynamics, interactions of large assemblies of intrinsically disordered proteins

Richard N Freiman, PhD

Transcriptional regulation in mammalian development and human disease

Maria Garcia-Moliner, MD

Mitochondria changes in cancer, LAM

Susan Gerbi, PhD

Molecular Biology, Cell Biology and Biochemistry

Philip Gruppuso
Philip Gruppuso, MD

mTOR, HCC, Phosphoproteomics, Myc

Stephen L Helfand, MD

Professor of Biology, Vice Chair of Neurology, Molecular genetics of aging and longevity.

Agnes Kane
Agnes Kane, MD, PhD

Asbestos carcinogenesis, Nanomaterials

Habibe Kurt
Habibe Kurt, MD

Hematology Oncology

Olin Liang, PhD

Core Director (Lentivirus); Endothelial-tohematopoietic transition, Stem Cell Biology

Shaolei Lu
Shaolei Lu, MD, PhD

Surgical pathology, Gastrointestinal pathology, Clinical Immunology

Sara Maleki
Sara Maleki, MD

Cytopathology, Morphology, Thyroid and other cancers

Eric Morrow
Eric Morrow, MD, PhD

Genetic screens, iPSCs, Neurobiology​

Jessica Plavicki
Jessica Plavicki, PhD

Homeobox genes, CNS angiogenesis, Zebrafish models

Peter Quesenberry
Peter Quesenberry, MD

TRDG Leader, Extracellular Vesicles, Hematological malignancies

Abrar Qureshi
Abrar Qureshi, MD, MPH

TRDG Leader, Skin cancer

Bharat Ramratnam
Bharat Ramratnam, MD

COBRE Center for Cancer Research Development

Jonathan Reichner
Jonathan Reichner, PhD

Neutrophil biology, Host defense against cancer

Jennifer Sanders
Jennifer Sanders, PhD

Liver cancer, Liver stem cells, Liver injury

James Sung
James Sung, MD

Breast and endometrial cancer GYN pathology

Nikos Tapinos
Nikos Tapinos, MD, PhD

CNS cancer, Epigenetics

Xiaobing Tian, PhD

Core Director (Organic Synthesis); Research Assistant Professor, Integrated stress response, Cell signaling, Myc, Puma, p53

Diana Treaba, MD

Leukemia, Lymphoma, Clinical pathology

Dilber Ece Uzun
Dilber Ece Uzun, PhD

Clinical bioinformatics, Drug absorption

Jack Wands, MD

Viral Hepatitis, Liver cancer, Biomarkers for HCC

Yihong Wang, MD, PhD

Breast cancer, miRNA, Wnt signaling

Li Juan Wang
Li Juan Wang, PhD

Clinical Pathology, GSK3, TNF, S100

Ashley E. Webb, PhD

Neural stem cell quiescence, aging, cognitive function, learning and memory, age-dependent diseases such as Alzheimer’s disease and vascular dementia

Ian Wong
Ian Wong, PhD

Cancer cell invasion, Phenotypic plasticity, 3D cultures, EMT, Heterogeneity

Evgeny Yakirevich, MD

Molecular markers, Survivin in Breast cancer, Glucocorticoid receptor

Wentian Yang
Wentian Yang, PhD

Kinases and phosphatases, Cartilage stem cells, Cell signaling, Differentiation

Elizabeth Yiru Wu
Elizabeth Yiru Wu, MD

Molecular correlates, Mitotic activity, BRAF CRC p53

Shengliang Zhang, MD, PhD

Core Director (Drug Discovery); Research Assistant Professor, ROS, ERK2, MDM2, p53

Tongzhang Zheng, ScD

Professor of Epidemiology