Research Interests: We are interested in evolution of brain function and behavior. Our primary model system is Drosophila, the fruit fly, for its powerful traditional and molecular genetics. Our main question is - how do genomes encode and regulate proteins involved in rapid electrical and chemical signaling in the brain, normally and in disease? Surprisingly, this has led us into studies of RNA editing, comparative genomics, small non-coding RNA, heterochromatin, evolution of RNA structure, and inherited neurological disorders.