Kelsey Huntington was awarded the NIH Ruth L. Kirschstein National Research Service Award (#NRSA) Individual Predoctoral Fellowship (#F31) by the National Cancer Institute (NCI) on her first-round grant application titled “Small-molecule Inhibition of Glycogen Synthase Kinase-3 Sensitizes Colorectal Cancer Cells and Stimulates Immune Cells to Bolster Immune Cell-mediated Tumor Cytotoxicity” that will fund the remainder of her PhD here at Brown University.

https://twitter.com/BrownUPathoGP

https://www.linkedin.com/posts/kelsey-huntington_nrsa-f31-eldeirylab-activity-6909164035045273600-_i_F

Two new publications involving Pathobiology graduate students, other El-DEIRY lab members, and collaborating faculty at Brown clinical Departments and Lifespan Hospitals.

Kelsey E Huntington, Anna Louie, Lanlan Zhou, Attila A Seyhan, Aaron WP Maxwell, Wafik S El-Deiry: Colorectal cancer extracellular acidosis decreases immune cell killing and is partially ameliorated by pH-modulating agents that modify tumor cell cytokine profiles. Am J Cancer Res 2022;12(1):138-151.

https://e-century.us/files/ajcr/12/1/ajcr0138692.pdf

Nicholas R Liguori, Ashley Sanchez Sevilla Uruchurtu, Leiqing Zhang, Abbas E Abbas, Young S Lee, Lanlan Zhou, Christopher G Azzoli, Wafik S El-Deiry: Preclinical studies with ONC201/TIC10 and lurbinectedin as a novel combination therapy in small cell lung cancer (SCLC). Am J Cancer Res 2022;12(2):729-743. 

https://e-century.us/files/ajcr/12/2/ajcr0138354.pdf

Dr. El-Deiry published a guest editorial in The Cancer Letter on March 4, 2022 entitled: 

"Ukraine Invasion: How the Cancer Community Can Help"

Project Title: FIA-Morehouse School of Medicine and the Legorreta Cancer Center at Brown University

The award is related to Diversity in Cancer Research Institutional Development. The American Cancer Society is grateful Brown University is allowing Dr. El-Deiry to accept this award to support ACS’s efforts to increase workforce diversity.

The Legorreta Cancer Center at Brown University has been approved for full membership in the Union for International Cancer Control (UICC)

The Legorreta Cancer Center at Brown University announces the awardees of the 2022 Pilot grant competition. These 10 one-year awards were made after applications were received from throughout Brown University and affiliated hospitals. The goal of the request for pilot grant applications was to encourage collaboration and basic-translational research across the academic medical center and within the Legorreta Cancer Center’s research programs in Cancer Biology, Cancer Therapeutics, and Population Science.  Thomas Bartnikas, MD, PhD,  Diana Treaba, MD, and Ece Uzun, PhD are part of the 10 faculty members who have been awarded the 2022 Pilot Funds.

2022 Pilot Award Winners

Dr. Eric Darling, Associate Professor of Medical Science was recently awarded a Research Experience for Teachers.  This is a $20,000 supplement to his NSF grant. These funds will support having two local high school teachers join Dr. Darling's lab in the summer and learn about interdisciplinary research. By the end of this experience, they will develop their own interdisciplinary exercise that can be implemented in the classroom to introduce high school students to how math/science subjects often integrate together.

Dr. Jeffrey Morgan's PLM paper was published in  Advanced Science (IF 16.8) and is being covered by a Brown press release: https://www.brown.edu/news/2022-02-01/fibrosis

Dr. Karl Kelsey has a new paper in Nature Communications:

Salas LA, Zhang Z, Koestler DC, Butler RA, Hansen HM, Molinaro AM, Wiencke JK, Kelsey KT, Christensen BC. (2021, In Press) Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profiling. Nat Comm (In Press). DOI: 10.1101/2021.04.11.439377

Dr. Weibiao Cao has had two abstracts accepted by the United States and Canadian Academy of Pathology (USCAP) to be presented in March, 2022 at the LA Convention Center.

Abstract #: 570
Abstract Title: Patterns of inflammatory cell infiltration in the lungs of patients with COVID-19, an autopsy study
Poster Board #: 117
Presentation Details: Poster Session on Tuesday, March 22, 2022 from 9:30 AM - 12:00 PM at the Los Angeles Convention Center in West Exhibit Hall A

Abstract #: 574
Abstract Title: Effect of the COVID-19 pandemic on autopsy rate
Poster Board #: 120
Presentation Details: Poster Session on Tuesday, March 22, 2022 from 9:30 AM - 12:00 PM at the Los Angeles Convention Center in West Exhibit Hall A