Ethan Balk, MD MPH, is Associate Professor (Research) in the Brown University School of Public Health. For about 15 years, his research has focused on systematic review, evidence based medicine, meta-analysis, study quality assessment, and evaluation of literature. He has led numerous comparative effectiveness reviews, evidence reports, technologies, and other systematic reviews for the Agency for Healthcare Research and Quality Evidence-base Practice Center program, for other federal and international agencies, and professional organizations. His reviews have covered a breadth of clinical medicine and nutrition topics and areas including cardiovascular disease, diabetes, kidney disease, surgical interventions, prevention, diagnostic tests, dietary supplements, fatty acid intake, and micronutrients, among others. For about 11 years, he collaborated with the KDOQI and KDIGO kidney disease guideline development organizations, leading evidence review teams conducting systematic reviews and training workgroup members in the development of evidence-based guidelines. For about 6 years he has also assisted the Society of Gynecologic Surgeons Systematic Review Group to develop systematic reviews and clinical practice recommendations.