NIOSH Pocket Guide to Chemical Hazards

o-Anisidine CAS 90-04-0
NH2C6H4OCH3 RTECS BZ5410000
Synonyms & Trade Names
ortho-Aminoanisole, 2-Anisidine, o-Methoxyaniline [Note: o-Anisidine has been used as a basis for many dyes.]
DOT ID & Guide
2431 153
Exposure
Limits
NIOSH REL: Ca 0.5 mg/m3 [skin] See Appendix A
OSHA PEL: TWA 0.5 mg/m3 [skin]
IDLH Ca [50 mg/m3] Conversion
Physical Description
Red or yellow, oily liquid with an amine-like odor. [Note: A solid below 41°F.]
MW: 123.2
BP: 437°F
FRZ: 41°F
Sol(77°F): 1%
VP: <0.1 mmHg
IP: 7.44 eV

Sp.Gr: 1.10
Fl.P(oc): 244°F
UEL: ?
LEL: ?

Class IIIB Combustible Liquid: Fl.P. at or above 200F.
Incompatibilities & Reactivities
Strong oxidizers
Measurement Methods
NIOSH 2514
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: Daily
Provide: Eyewash, Quick drench
First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Headache, dizziness; cyanosis; red blood cell Heinz bodies; [potential occupational carcinogen]
Target Organs Blood, kidneys, liver, cardiovascular system, central nervous system

Cancer Site [in animals: tumors of the thyroid gland, bladder & kidneys]
See also: INTRODUCTION