Publications

2019

Metabolism-induced oxidative stress and DNA damage selectively trigger genome instability in polyploid fungal cells. Thomson GJ, Hernon C, Austriaco N, Shapiro RS, Belenky P, Bennett RJ. EMBO J. 2019 Aug 26:e101597. doi: 10.15252/embj.2019101597. [Epub ahead of print] PMID: 31448850

Single cell RNA-seq in the sea urchin embryo show marked cell-type specificity in the Delta/Notch pathway. Foster S, Teo YV, Neretti N, Oulhen N, Wessel GM.

Mol Reprod Dev. 2019 Aug;86(8):931-934. doi: 10.1002/mrd.23181. Epub 2019 Jun 14. PMID: 31199038

More than Microtubules: The Structure and Function of the Subpellicular Array in Trypanosomatids. Sinclair AN, de Graffenried CL. Trends Parasitol. 2019 Aug 27. pii: S1471-4922(19)30189-8. doi: 10.1016/j.pt.2019.07.008. [Epub ahead of print] Review. PMID: 31471215

Genetic modification of closely related Candida species. Mancera, E., Frazer, C., Porman, A. M., Ruiz-Castro, S., Johnson, A. D. and Bennett, R. J. 2019. Front Microbiol, 10:357. PMID:30941104.

Hemizygosity enables a mutational transition governing fungal virulence and commensalism. Liang, S. H., Anderson, M. Z., Hirakawa, M. P., Wang, J. M., Frazer, C., Alaalm, L. M., Thomson, G. J., Ene, I. V. and Bennett, R. J. 2019. Cell Host Microbe, PMID:30824263.

MMSplice: modular modeling improves the predictions of genetic variant effects on splicing. Cheng, J., Nguyen, T. Y. D., Cygan, K. J., Celik, M. H., Fairbrother, W. G., Avsec, Z. and Gagneur, J. 2019. Genome Biol, 20:48. PMID:30823901.

Molecular interactions underlying liquid-liquid phase separation of the FUS low complexity domain. Murthy, A., Dignon, G., Kan, Y., Zerze, G. H., Parekh, S., Mittal, J. and Fawzi, N. L. 2019. Nature Structural and Molecular Biology.

Iterative subtraction facilitates automated, quantitative analysis of multiple pollen tube growth features. Ponvert, N., Goldberg, J., Leydon, A. and Johnson, M. A. 2019. Plant Reprod, 32:45-54. PMID:30543045.

Diverse genome topologies characterize dosage compensation across species. Jordan, W., 3rd, Rieder, L. E. and Larschan, E. 2019. Trends Genet, PMID:30808531.

L1 drives IFN in senescent cells and promotes age-associated inflammation. De Cecco, M., Ito, T., Petrashen, A. P., Elias, A. E., Skvir, N. J., Criscione, S. W., Caligiana, A., Brocculi, G., Adney, E. M., Boeke, J. D., Le, O., Beausejour, C., Ambati, J., Ambati, K., Simon, M., Seluanov, A., Gorbunova, V., Slagboom, P. E., Helfand, S. L., Neretti, N. and Sedivy, J. M. 2019. Nature, 566:73-8. PMID:30728521.

SLC1A5 glutamine transporter is a target of MYC and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice. Zhao, X., Petrashen, A. P., Sanders, J. A., Peterson, A. L. and Sedivy, J. M. 2019. Aging Cell, e12947. PMID:30909319.

Trafficking of the human ether-a-go-go-related gene (hERG) potassium channel is regulated by the ubiquitin ligase rififylin (RFFL). Roder, K., Kabakov, A., Moshal, K. S., Murphy, K. R., Xie, A., Dudley, S., Turan, N. N., Lu, Y., MacRae, C. A. and Koren, G. 2019. J Biol Chem, 294:351-60. PMID:30401747.

Identifying gene expression from single cells to single genes. Oulhen, N., Foster, S., Wray, G. and Wessel, G. 2019. Methods Cell Biol, 151:127-58. PMID:30948004.

Circuit dysfunction in SOD1-ALS model first detected in sensory feedback prior to motor neuron degeneration is alleviated by BMP signaling. Held, A., Major, P., Sahin, A., Reenan, R., Lipscombe, D. and Wharton, K. A. 2019. Journal of Neuroscience, PMID:30659087.

Meta-analysis of genetic modifiers reveals candidate dysregulated pathways in Amyotrophic Lateral Sclerosis. Yanagi, K. S., Wu, Z., Amaya, J., Chapkis, N., Duffy, A. M., Hajdarovic, K. H., Held, A., Mathur, A. D., Russo, K., Ryan, V. H., Steinert, B. L., Whitt, J. P., Fallon, J. R., Fawzi, N. L., Lipscombe, D., Reenan, R. A., Wharton, K. A. and Hart, A. C. 2019. Neuroscience, 396:A3-a20. PMID:30594291.

2018

Characterization of PdCP1, a serine carboxypeptidase from Pseudogymnoascus destructans, the causal agent of White-nose Syndrome. Beekman, C., Jiang, Z., Suzuki, B. M., Palmer, J. M., Lindner, D. L., O'Donoghue, A. J., Knudsen, G. M. and Bennett, R. J. 2018. Biol Chem, PMID:30367778.

Identification of TOEFAZ1-interacting proteins reveals key regulators of Trypanosoma brucei cytokinesis. Hilton, N. A., Sladewski, T. E., Perry, J. A., Pataki, Z., Sinclair-Davis, A. N., Muniz, R. S., Tran, H. L., Wurster, J. I., Seo, J. and de Graffenried, C. L. 2018. Mol Microbiol, PMID:29781112.

TbSmee1 regulates hook complex morphology and the rate of flagellar pocket uptake in Trypanosoma brucei. Perry, J. A., Sinclair-Davis, A. N., McAllaster, M. R. and de Graffenried, C. L. 2018. Mol Microbiol, 107:344-62. PMID:29178204.

Initiating base excision repair in chromatin. Kennedy, E. E., Caffrey, P. J. and Delaney, S. 2018. DNA Repair (Amst), 71:87-92. PMID:30170831.

Human oxoguanine glycosylase 1 removes solution accessible 8-Oxo-7,8-dihydroguanine lesions from globally substituted nucleosomes except in the dyad region. Bilotti, K., Tarantino, M. E. and Delaney, S. 2018 Biochemistry, 57:1436-9. PMID:29341606.

Nucleosomes and the three glycosylases: High, medium, and low levels of excision by the uracil DNA glycosylase superfamily. Tarantino, M. E., Dow, B. J., Drohat, A. C. and Delaney, S. 2018. DNA Repair (Amst), 72:56-63. PMID:30268365.

Inborn errors of RNA lariat metabolism in humans with brainstem viral infection. Zhang, S. Y., Clark, N. E., Freije, C. A., Pauwels, E., Taggart, A. J., Okada, S., Mandel, H., Garcia, P., Ciancanelli, M. J., Biran, A., Lafaille, F. G., Tsumura, M., Cobat, A., Luo, J., Volpi, S., Zimmer, B., Sakata, S., Dinis, A., Ohara, O., Garcia Reino, E. J., Dobbs, K., Hasek, M., Holloway, S. P., McCammon, K., Hussong, S. A., DeRosa, N., Van Skike, C. E., Katolik, A., Lorenzo, L., Hyodo, M., Faria, E., Halwani, R., Fukuhara, R., Smith, G. A., Galvan, V., Damha, M. J., Al-Muhsen, S., Itan, Y., Boeke, J. D., Notarangelo, L. D., Studer, L., Kobayashi, M., Diogo, L., Fairbrother, W. G., Abel, L., Rosenberg, B. R., Hart, P. J., Etzioni, A. and Casanova, J. L. 2018. Cell, 172:952-65.e18. PMID:29474921.

Changes in the process of alternative RNA splicing results in soluble B and T lymphocyte attenuator with biological and clinical implications in critical illness. Monaghan, S. F., Banerjee, D., Chung, C. S., Lomas-Neira, J., Cygan, K. J., Rhine, C. L., Fairbrother, W. G., Heffernan, D. S., Levy, M. M., Cioffi, W. G. and Ayala, A. 2018. Mol Med, 24:32. PMID:30134817.

The RNA spliceosome in critical illness: U1-70K as a potential therapeutic target. Monaghan, S. F., Cygan, K. J., Lomas-Neirra, J., Chung, C. S., Heffernan, D. S., Cioffi, W. G., Harrington, E. O., Fairbrother, W. G. and Ayala, A. 2018. Shock, 49:33-. PMID:WOS:000441343800054.

Hereditary cancer genes are highly susceptible to splicing mutations. Rhine, C. L., Cygan, K. J., Soemedi, R., Maguire, S., Murray, M. F., Monaghan, S. F. and Fairbrother, W. G. 2018. PLoS Genet, 14:e1007231. PMID:29505604.

Changes in the process of alternative RNA splicing results in soluble B and T lymphocyte attenuator with biological and clinical implications in critical illness. Monaghan, S. F., Banerjee, D., Chung, C. S., Lomas-Neira, J., Cygan, K. J., Rhine, C. L., Fairbrother, W. G., Heffernan, D. S., Levy, M. M., Cioffi, W. G. and Ayala 2018., A. Mol Med, 24:32. PMID:30134817.

Hereditary cancer genes are highly susceptible to splicing mutations. Rhine, C. L., Cygan, K. J., Soemedi, R., Maguire, S., Murray, M. F., Monaghan, S. F. and Fairbrother, W. G. 2018. PLoS Genet, 14:e1007231. PMID:29505604.

Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis. Fratta, P., Sivakumar, P., Humphrey, J., Lo, K., Ricketts, T., Oliveira, H., Brito-Armas, J. M., Kalmar, B., Ule, A., Yu, Y., Birsa, N., Bodo, C., Collins, T., Conicella, A. E., Mejia Maza, A., Marrero-Gagliardi, A., Stewart, M., Mianne, J., Corrochano, S., Emmett, W., Codner, G., Groves, M., Fukumura, R., Gondo, Y., Lythgoe, M., Pauws, E., Peskett, E., Stanier, P., Teboul, L., Hallegger, M., Calvo, A., Chio, A., Isaacs, A. M., Fawzi, N. L., Wang, E., Housman, D. E., Baralle, F., Greensmith, L., Buratti, E., Plagnol, V., Fisher, E. M. and Acevedo-Arozena, A. 2018. EMBO Journal, 37:PMID:29764981.

Lysines in the RNA polymerase II C-terminal domain contribute to TAF15 fibril recruitment. Janke, A. M., Seo, D. H., Rahmanian, V., Conicella, A. E., Mathews, K. L., Burke, K. A., Mittal, J. and Fawzi, N. L. 2018. Biochemistry, 57:2549-63. PMID:28945358.

Differential occupancy of two GA-binding proteins promotes targeting of the Drosophila dosage compensation complex to the male X chromosome. Kaye, E. G., Booker, M., Kurland, J. V., Conicella, A. E., Fawzi, N. L., Bulyk, M. L., Tolstorukov, M. Y. and Larschan, E. 2018. Cell Rep, 22:3227-39. PMID:29562179.

Mechanistic view of hnRNPA2 low-complexity domain structure, interactions, and phase separation altered by mutation and arginine methylation. Ryan, V. H., Dignon, G. L., Zerze, G. H., Chabata, C. V., Silva, R., Conicella, A. E., Amaya, J., Burke, K. A., Mittal, J. and Fawzi, N. L. 2018. Mol Cell, 69:465-79.e7. PMID:29358076.

A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing. Wang, A., Conicella, A. E., Schmidt, H. B., Martin, E. W., Rhoads, S. N., Reeb, A. N., Nourse, A., Ramirez Montero, D., Ryan, V. H., Rohatgi, R., Shewmaker, F., Naik, M. T., Mittag, T., Ayala, Y. M. and Fawzi, N. L. 2018. EMBO Journal, 37:PMID:29438978.

Lysines in the RNA Polymerase II C-Terminal Domain Contribute to TAF15 Fibril Recruitment. Janke, A. M., Seo, D. H., Rahmanian, V., Conicella, A. E., Mathews, K. L., Burke, K. A., Mittal, J. and Fawzi, N. L. 2018. Biochemistry, 57:2549-63. PMID:28945358.

Primordial Follicle. Gura M.A., Freiman R.N. 2018. Encyclopedia of Reproduction Second Edition: 65-71. Elsevier

Surviving deadly lung infections: Innate host tolerance mechanisms in the pulmonary system. Crane, M. J., Lee, K. M., FitzGerald, E. S. and Jamieson, A. M. 2018. Front Immunol, 9:1421. PMID:29988424.

Iterative subtraction facilitates automated, quantitative analysis of multiple pollen tube growth features. Ponvert, N., Goldberg, J., Leydon, A. and Johnson, M. A. 2018. Plant Reprod, PMID:30543045.

Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes. Fedry, J.*, Forcina, J.*, Legrand, P., Pehau-Arnaudet, G., Haouz, A., Johnson, M., Rey, F. A. and Krey, T. 2018. PLoS Biol, 16:e2006357. PMID:30102690.  *co-first authors

Iterative subtraction facilitates automated, quantitative analysis of multiple pollen tube growth features. Ponvert, N., Goldberg, J., Leydon, A. and Johnson, M. A. 2018. Plant Reprod, PMID:30543045.

A Universal Scaling Relation for Defining Power Spectral Bands in Mammalian Heart Rate Variability Analysis. Behar, J. A., Rosenberg, A. A., Shemla, O., Murphy, K. R., Koren, G., Billman, G. E. and Yaniv, Y. 2018. Front Physiol, 9:1001. PMID:30116198.

Trafficking of the human ether-a-go-go-related gene (hERG) potassium channel is regulated by the ubiquitin ligase rififylin (RFFL). Roder, K., Kabakov, A., Moshal, K. S., Murphy, K. R., Xie, A., Dudley, S., Turan, N. N., Lu, Y., MacRae, C. A. and Koren, G. 2018. J Biol Chem, PMID:30401747.

Differential occupancy of two GA-binding proteins promotes targeting of the Drosophila dosage compensation complex to the male X chromosome. Kaye, E. G., Booker, M., Kurland, J. V., Conicella, A. E., Fawzi, N. L., Bulyk, M. L., Tolstorukov, M. Y. and Larschan, E. 2018. Cell Rep, 22:3227-39. PMID:29562179.

Fluorescence in situ hybridization of cryosectioned Xenopus oocytes. Neil, C. R. and Mowry, K. 2018. Cold Spring Harb Protoc, PMID:29437997.

Whole-mount immunofluorescence for visualizing endogenous protein and injected RNA in Xenopus oocytes. Jeschonek, S. P. and Mowry, K. L. 2018. Cold Spring Harb Protoc, PMID:29321279.

Modeling microtubule-based transport and anchoring of mRNA.  Ciocanel, M.V., Sanstede, B., Jeschonek, S.P. and Mowry, K.L. (2018). SIAM J. Appl. Dyn. Syst. 17:  2855-81.

The three-dimensional organization of the genome in cellular senescence and age-associated diseases. Evans, S., Horrell, J. and Neretti, N. 2018. Semin Cell Dev Biol, PMID:30031215.

Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways. Ito, T., Teo, Y. V., Evans, S. A., Neretti, N. and Sedivy, J. M. 2018. Cell Rep, 22:3480-92. PMID:29590617.

Drosophila insulin-like peptides DILP2 and DILP5 differentially stimulate cell signaling and glycogen phosphorylase to regulate longevity. Post, S., Karashchuk, G., Wade, J. D., Sajid, W., De Meyts, P. and Tatar, M. 2018. Front Endocrinol (Lausanne), 9:245. PMID:29892262.

Drosophila insulin-like peptide dilp1 increases lifespan and glucagon-like Akh expression epistatic to dilp2. Post, S., Liao, S., Yamamoto, R., Veenstra, J. A., Nassel, D. R. and Tatar, M. 2018. Aging Cell, e12863. PMID:30511458.

FGF binding proteins (FGFBPs): Modulators of FGF signaling in the developing, adult, and stressed nervous system. Taetzsch, T., Brayman, V. L. and Valdez, G. 2018. Biochim Biophys Acta Mol Basis Dis, 1864:2983-91. PMID:29902550.

Alpha-Motor neurons are spared from aging while their synaptic inputs degenerate in monkeys and mice. Maxwell, N., Castro, R. W., Sutherland, N. M., Vaughan, K. L., Szarowicz, M. D., de Cabo, R., Mattison, J. A. and Valdez, G. 2018. Aging Cell, 17:PMID:29397579.

Regulation of FOXO factors in mammalian cells. Brown, A. K. and Webb, A. E. 2018. Curr Top Dev Biol, 127:165-92. PMID:29433737.

Nodal induces sequential restriction of germ cell factors during primordial germ cell specification. Fresques, T. M. and Wessel, G. M. 2018. Development, 145:PMID:29358213.

Le, V., Anderson, E., Akiyama, T. and Wharton, K. A. 2018. Bone, 109:192-200. PMID:29128351.

JAK/STAT signaling prevents excessive apoptosis to ensure maintenance of the interfollicular stalk critical for Drosophila oogenesis. Borensztejn, A., Mascaro, A. and Wharton, K. A. 2018. Developmental Biology, PMID:29571611.

Corrigendum to "JAK/STAT signaling prevents excessive apoptosis to ensure maintenance of the interfollicular stalk critical for Drosophila oogenesis" Borensztejn, A., Mascaro, A. and Wharton, K. A. 2018. [Dev. Biol. 438 (2018) 1-9]. Developmental Biology, PMID:30309615.

2017

Program cell death receptor-1-mediated invariant natural killer T-cell control of peritoneal macrophage modulates survival in neonatal sepsis. Fallon, E. A., Chun, T. T., Young, W. A., Gray, C., Ayala, A. and Heffernan, D. S. 2017. Front Immunol, 8:1469. PMID:29209308.

Development of a CRISPR-Cas9 system for efficient genome editing of Candida lusitaniae.  Norton, E. L., Sherwood, R. K. and Bennett, R. J. 2017. mSphere, 2:PMID:28657072.

Negative regulation of filamentous growth in Candida albicans. Regan, H., Scaduto, C., Hirakawa, M. P., Gunsalus, K., Correia-Mesquita, T. O., Sun, Y., Chen, Y., Kumamoto, C. A., Bennett, R. and Whiteway, M. 2017. by Dig1p. Mol Microbiol, PMID:28657681.

Epigenetic control of pheromone MAPK signaling determines sexual fecundity in Candida albicans. Scaduto, C. M., Kabrawala, S., Thomson, G. J., Scheving, W., Ly, A., Anderson, M. Z., Whiteway, M. and Bennett, R. J. 2017. Proc Natl Acad Sci U S A, 114:13780-5. PMID:29255038.

Epigenetic control of pheromone MAPK signaling determines sexual fecundity in Candida albicans. Scaduto, C. M., Kabrawala, S., Thomson, G. J., Scheving, W., Ly, A., Anderson, M. Z., Whiteway, M. and Bennett, R. J. 2017. Proc Natl Acad Sci U S A, 114:13780-5. PMID:29255038.

Lacrimal gland NK cells ere developmentally and functionally similar to conventional NK cells. Erick, T., Grigoryan, L. and Brossay, L. 2017. Immunohorizons, 1:2-9. PMID:28966997.

The loss and recovery of vertebrate vision examined in microplates. Thorn, R. J., Clift, D. E., Ojo, O., Colwill, R. M. and Creton, R. 2017. PLoS One, 12:e0183414. PMID:28817700.

A unified approach towards Trypanosoma brucei functional genomics using Gibson assembly. McAllaster, M. R., Sinclair-Davis, A. N., Hilton, N. A. and de Graffenried, C. L. 2016. Mol Biochem Parasitol, PMID:27496178.

TbSmee1 regulates hook complex morphology and the rate of flagellar pocket uptake in Trypanosoma brucei.Perry, J. A., Sinclair-Davis, A. N., McAllaster, M. R. and de Graffenried, C. L. 2017. Mol Microbiol, PMID:29178204.

Functional analysis of TOEFAZ1 uncovers protein domains essential for cytokinesis in Trypanosoma brucei. Sinclair-Davis, A. N., McAllaster, M. R. and de Graffenried, C. L. 2017. J Cell Sci, PMID:28993462.

Human OGG1 activity in nucleosomes is facilitated by transient unwrapping of DNA and is influenced by the local histone environment. Bilotti, K., Kennedy, E. E., Li, C. and Delaney, S. 2017. DNA Repair (Amst), 59:1-8. PMID:28892740.

Widespread intra-dependencies in the removal of introns from human transcripts. Kim, S. W., Taggart, A. J., Heintzelman, C., Cygan, K. J., Hull, C. G., Wang, J., Shrestha, B. and Fairbrother, W. G. 2017. Nucleic Acids Res, 45:9503-13. PMID:28934498.

The effects of structure on pre-mRNA processing and stability. Soemedi, R., Cygan, K. J., Rhine, C. L., Glidden, D. T., Taggart, A. J., Lin, C. L., Fredericks, A. M. and Fairbrother, W. G. 2017. Methods, 125:36-44. PMID:28595983.

Large-scale analysis of branchpoint usage across species and cell lines. Taggart, A. J., Lin, C. L., Shrestha, B., Heintzelman, C., Kim, S. and Fairbrother, W. G. 2017.  Genome Res, PMID:28119336.

Spliceman2: a computational web server that predicts defects in pre-mRNA splicing. Cygan, K. J., Sanford, C. H. and Fairbrother, W. G. 2017. Bioinformatics, 33:2943-5. PMID:28911038.

Defective splicing of the RB1 transcript is the dominant cause of retinoblastomas. Cygan, K. J., Soemedi, R., Rhine, C. L., Profeta, A., Murphy, E. L., Murray, M. F. and Fairbrother, W. G. 2017. Hum Genet, PMID:28780672.

Widespread intra-dependencies in the removal of introns from human transcripts. Kim, S. W., Taggart, A. J., Heintzelman, C., Cygan, K. J., Hull, C. G., Wang, J., Shrestha, B. and Fairbrother, W. G. 2017. Nucleic Acids Res, 45:9503-13. PMID:28934498.

The effects of structure on pre-mRNA processing and stability. Soemedi, R., Cygan, K. J., Rhine, C. L., Glidden, D. T., Taggart, A. J., Lin, C. L., Fredericks, A. M. and Fairbrother, W. G. 2017. Methods, 125:36-44. PMID:28595983.

Pathogenic variants that alter protein code often disrupt splicing. Soemedi, R., Cygan, K. J., Rhine, C. L., Wang, J., Bulacan, C., Yang, J., Bayrak-Toydemir, P., McDonald, J. and Fairbrother, W. G. 2017. Nat Genet, 49:848-55. PMID:28416821.

The effects of structure on pre-mRNA processing and stability. Soemedi, R., Cygan, K. J., Rhine, C. L., Glidden, D. T., Taggart, A. J., Lin, C. L., Fredericks, A. M. and Fairbrother, W. G. 2017. Methods, 125:36-44. PMID:28595983.

Defective splicing of the RB1 transcript is the dominant cause of retinoblastomas. Cygan, K. J., Soemedi, R., Rhine, C. L., Profeta, A., Murphy, E. L., Murray, M. F. and Fairbrother, W. G. 2017. Hum Genet, PMID:28780672.

The effects of structure on pre-mRNA processing and stability. Soemedi, R., Cygan, K. J., Rhine, C. L., Glidden, D. T., Taggart, A. J., Lin, C. L., Fredericks, A. M. and Fairbrother, W. G. 2017. Methods, 125:36-44. PMID:28595983.

Pathogenic variants that alter protein code often disrupt splicing. Soemedi, R., Cygan, K. J., Rhine, C. L., Wang, J., Bulacan, C., Yang, J., Bayrak-Toydemir, P., McDonald, J. and Fairbrother, W. G. 2017. Nat Genet, 49:848-55. PMID:28416821.

Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity. Monahan, Z., Ryan, V. H., Janke, A. M., Burke, K. A., Rhoads, S. N., Zerze, G. H., O'Meally, R., Dignon, G. L., Conicella, A. E., Zheng, W., Best, R. B., Cole, R. N., Mittal, J., Shewmaker, F. and Fawzi, N. L. 2017. EMBO Journal, PMID:28790177.

The molecular dialog between flowering plant reproductive partners defined by SNP-informed RNA-sequencing. Leydon, A. R., Weinreb, C., Venable, E., Reinders, A., Ward, J. M. and Johnson, M. A. 2017. Plant Cell, 29:984-1006. PMID:28400492.

Transporters involved in pH and K+ homeostasis affect pollen wall formation, male fertility, and embryo development. Padmanaban, S., Czerny, D. D., Levin, K. A., Leydon, A. R., Su, R. T., Maugel, T. K., Zou, Y., Chanroj, S., Cheung, A. Y., Johnson, M. A. and Sze, H. 2017. J Exp Bot, PMID:28338823.

SK channel enhancers attenuate Ca2+-dependent arrhythmia in hypertrophic hearts by regulating mito-ROS-dependent oxidation and activity of RyR. Kim, T. Y., Terentyeva, R., Roder, K. H., Li, W., Liu, M., Greener, I., Hamilton, S., Polina, I., Murphy, K. R., Clements, R. T., Dudley, S. C., Jr., Koren, G., Choi, B. R. and Terentyev, D. 2017. Cardiovasc Res, 113:343-53. PMID:28096168.

A novel method of standardized myocardial infarction in aged rabbits. Morrissey, P. J.*, Murphy, K. R.*, Daley, J. M., Schofield, L., Turan, N. N., Arunachalam, K., Abbott, J. D. and Koren, G. 2017. Am J Physiol Heart Circ Physiol, 312:H959-h67. PMID:28213402. *co-first authors

Histone locus regulation by the Drosophila dosage compensation adaptor protein CLAMP. Rieder, L. E., Koreski, K. P., Boltz, K. A., Kuzu, G., Urban, J. A., Bowman, S. K., Zeidman, A., Jordan, W. T., 3rd, Tolstorukov, M. Y., Marzluff, W. F., Duronio, R. J. and Larschan, E. N. 2017. Genes Dev, 31:1494-508. PMID:28838946.

Enhanced chromatin accessibility of the dosage compensated Drosophila male X-chromosome requires the CLAMP zinc finger protein. Urban, J., Kuzu, G., Bowman, S., Scruggs, B., Henriques, T., Kingston, R., Adelman, K., Tolstorukov, M. and Larschan, E. 2017. PLoS One, 12:e0186855. PMID:29077765.

The Drosophila CLAMP protein associates with diverse proteins on chromatin. Urban, J. A., Urban, J. M., Kuzu, G. and Larschan, E. N. 2017. PLoS One, 12:e0189772. PMID:29281702.

Drosophila dosage compensation loci associate with a boundary-forming insulator complex. Kaye, E. G., Kurbidaeva, A., Wolle, D., Aoki, T., Schedl, P. and Larschan, E. 2017. Molecular and Cellular Biology, 37:PMID:28784719.

Histone locus regulation by the Drosophila dosage compensation adaptor protein CLAMP. Rieder, L. E., Koreski, K. P., Boltz, K. A., Kuzu, G., Urban, J. A., Bowman, S. K., Zeidman, A., Jordan, W. T., 3rd, Tolstorukov, M. Y., Marzluff, W. F., Duronio, R. J. and Larschan, E. N. 2017. Genes Dev, 31:1494-508. PMID:28838946.

The essential Drosophila CLAMP protein differentially regulates non-coding roX RNAs in male and females. Urban, J. A., Doherty, C. A., Jordan, W. T., 3rd, Bliss, J. E., Feng, J., Soruco, M. M., Rieder, L. E., Tsiarli, M. A. and Larschan, E. N. 2017. Chromosome Res, 25:101-13. PMID:27995349.

Analysis of active transport by fluorescence recovery after photobleaching. Ciocanel, M. V., Kreiling, J. A., Gagnon, J. A., Mowry, K. L. and Sandstede, B. 2017. Biophys J, 112:1714-25. PMID:28445762.

GINOM: A statistical framework for assessing interval overlap of multiple genomic features. Bryner, D., Criscione, S., Leith, A., Huynh, Q., Huffer, F. and Neretti, N. 2017. PLoS Comput Biol, 13:e1005586. PMID:28617797.

Highly reproducible improved label-free quantitative analysis of cellular phosphoproteome by optimization of LC-MS/MS gradient and analytical column construction. Ahsan, N., Belmont, J., Chen, Z., Clifton, J. G. and Salomon, A. R. 2017. J Proteomics, PMID:28634120.

A PLC-gamma1 feedback pathway regulates Lck substrate phosphorylation at the T-cell receptor and SLP-76 complex. Belmont, J., Gu, T., Mudd, A. and Salomon, A. R. 2017. J Proteome Res, 16:2729-42. PMID:28644030.

Drosophila Kruppel homolog 1 represses lipolysis through interaction with dFOXO. Kang, P., Chang, K., Liu, Y., Bouska, M., Birnbaum, A., Karashchuk, G., Thakore, R., Zheng, W., Post, S., Brent, C. S., Li, S., Tatar, M. and Bai, H. 2017. Sci Rep, 7:16369. PMID:29180716.

Total solid-phase synthesis of biologically active Drosophila insulin-like peptide 2 (DILP2). Lin, F., Hossain, M. A., Post, S., Karashchuk, G., Tatar, M., De Meyts, P. and Wade, J. D. 2017. Australian Journal of Chemistry, 70:208-12. PMID:WOS:000395050500011.

Neuronal functions of FOXO/DAF-16. Kim, S. Y. and Webb, A. E. 2017. Nutr Healthy Aging, 4:113-26. PMID:28447066.

Protein kinase A activity leads to the extension of the acrosomal process in starfish sperm. Niikura, K., Alam, M. S., Naruse, M., Jimbo, M., Moriyama, H., Reich, A., Wessel, G. M. and Matsumoto, M. 2017. Mol Reprod Dev, PMID:28462533.

Transient translational quiescence in primordial germ cells. Oulhen, N., Swartz, S. Z., Laird, J., Mascaro, A. and Wessel, G. 2017. Development, PMID:28235822.

Alternative cleavage of the bone morphogenetic protein (BMP), Gbb, produces ligands with distinct developmental functions and receptor preferences. Anderson, E. N. and Wharton, K. A. 2017. J Biol Chem, 292:19160-78. PMID:28924042.

Drosophila models of FOP provide mechanistic insight. Le, V., Anderson, E., Akiyama, T. and Wharton, K. A. 2017. Bone, PMID:29128351.

Human SOD1 ALS mutations in a Drosophila knock-in model cause severe phenotypes and reveal dosage-sensitive gain- and loss-of-function components. Sahin, A., Held, A., Bredvik, K., Major, P., Achilli, T. M., Kerson, A. G., Wharton, K., Stilwell, G. and Reenan, R. 2017. Genetics, 205:707-23. PMID:27974499.

20S immunoproteasomes remove formaldehyde-damaged cytoplasmic proteins suppressing caspase-independent cell death. Ortega-Atienza, S., Krawic, C., Watts, L., McCarthy, C., Luczak, M. W. and Zhitkovich, A. 2017. Sci Rep, 7:654. PMID:28381880.

2016

Phenotypic plasticity regulates Candida albicans interactions and virulence in the vertebrate host. Mallick, E. M., Bergeron, A. C., Jones, S. K., Jr., Newman, Z. R., Brothers, K. M., Creton, R., Wheeler, R. T. and Bennett, R. J. 2016. Front Microbiol, 7:780. PMID:27303374.

A multistate toggle switch defines fungal cell fates and Is regulated by synergistic genetic cues. Anderson, M. Z., Porman, A. M., Wang, N., Mancera, E., Huang, D., Cuomo, C. A. and Bennett, R. J. 2016. PLoS Genet, 12:e1006353. PMID:27711197.

NFIL3 expression distinguishes tissue-resident NK cells and conventional NK-like cells in the mouse submandibular glands. Erick, T. K., Anderson, C. K., Reilly, E. C., Wands, J. R. and Brossay, L. 2016. Journal of Immunology, 197:2485-91. PMID:27521341.

Phenotype and functions of conventional and non-conventional NK cells. Erick, T. K. and Brossay, L. 2016. Curr Opin Immunol, 38:67-74. PMID:26706497.

RNA structure in splicing: An evolutionary perspective. Lin, C. L., Taggart, A. J. and Fairbrother, W. G. 2016. RNA Biol, 13:766-71. PMID:27454491.

RNA structure replaces the need for U2AF2 in splicing. Lin, C. L., Taggart, A. J., Lim, K. H., Cygan, K. J., Ferraris, L., Creton, R., Huang, Y. T. and Fairbrother, W. G. 2016. Genome Res, 26:12-23. PMID:26566657.

RNA structure replaces the need for U2AF2 in splicing. Lin, C. L., Taggart, A. J., Lim, K. H., Cygan, K. J., Ferraris, L., Creton, R., Huang, Y. T. and Fairbrother, W. G. 2016. Genome Res, 26:12-23. PMID:26566657.

The importance of p53 pathway genetics in inherited and somatic cancer genomes. Stracquadanio, G., Wang, X., Wallace, M. D., Grawenda, A. M., Zhang, P., Hewitt, J., Zeron-Medina, J., Castro-Giner, F., Tomlinson, I. P., Goding, C. R., Cygan, K. J., Fairbrother, W. G., Thomas, L. F., Saetrom, P., Gemignani, F., Landi, S., Schuster-Bockler, B., Bell, D. A. and Bond, G. L. 2016. Nat Rev Cancer, 16:251-65. PMID:27009395.

ALS mutations disrupt phase separation mediated by alpha-helical structure in the TDP-43 low-complexity C-terminal domain. Conicella, A. E., Zerze, G. H., Mittal, J. and Fawzi, N. L. 2016. Structure, PMID:27545621.

TAF4b regulates oocyte-specific genes essential for meiosis. Grive, K. J., Gustafson, E. A., Seymour, K. A., Baddoo, M., Schorl, C., Golnoski, K., Rajkovic, A., Brodsky, A. S. and Freiman, R. N. 2016. PLoS Genet, 12:e1006128. PMID:27341508.

A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan. Jones, B. C., Wood, J. G., Chang, C., Tam, A. D., Franklin, M. J., Siegel, E. R. and Helfand, S. L. 2016. Nat Commun, 7:13856. PMID:28000665.

Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila. Wood, J. G., Jones, B. C., Jiang, N., Chang, C., Hosier, S., Wickremesinghe, P., Garcia, M., Hartnett, D. A., Burhenn, L., Neretti, N. and Helfand, S. L. 2016. Proc Natl Acad Sci U S A, 113:11277-82. PMID:27621458.

MNase titration reveals differences between nucleosome occupancy and chromatin accessibility. Mieczkowski, J., Cook, A., Bowman, S. K., Mueller, B., Alver, B. H., Kundu, S., Deaton, A. M., Urban, J. A., Larschan, E., Park, P. J., Kingston, R. E. and Tolstorukov, M. Y. 2016. Nat Commun, 7:11485. PMID:27151365.

The essential Drosophila CLAMP protein differentially regulates non-coding roX RNAs in male and females. Urban, J. A., Doherty, C. A., Jordan, W. T., 3rd, Bliss, J. E., Feng, J., Soruco, M. M., Rieder, L. E., Tsiarli, M. A. and Larschan, E. N. 2016. Chromosome Res, PMID:27995349.

Expansion of GA dinucleotide repeats increases the density of CLAMP binding sites on the X-chromosome to promote Drosophila dosage compensation. Kuzu, G., Kaye, E. G., Chery, J., Siggers, T., Yang, L., Dobson, J. R., Boor, S., Bliss, J., Liu, W., Jogl, G., Rohs, R., Singh, N. D., Bulyk, M. L., Tolstorukov, M. Y. and Larschan, E. 2016. PLoS Genet, 12:e1006120. PMID:27414415.

The essential Drosophila CLAMP protein differentially regulates non-coding roX RNAs in male and females. Urban, J. A., Doherty, C. A., Jordan, W. T., 3rd, Bliss, J. E., Feng, J., Soruco, M. M., Rieder, L. E., Tsiarli, M. A. and Larschan, E. N. 2016. Chromosome Res, PMID:27995349.

Using in vivo imaging to measure RNA mobility in Xenopus laevis oocytes. Powrie, E. A., Ciocanel, V., Kreiling, J. A., Gagnon, J. A., Sandstede, B. and Mowry, K. L. 2016. Methods, 98:60-5. PMID:26546269.

Reorganization of chromosome architecture in replicative cellular senescence. Criscione, S. W., De Cecco, M., Siranosian, B., Zhang, Y., Kreiling, J. A., Sedivy, J. M. and Neretti, N. 2016. Sci Adv, 2:e1500882. PMID:26989773.

The Chromatin Landscape of Cellular Senescence. Criscione, S. W., Teo, Y. V. and Neretti, N. 2016. Trends Genet, 32:751-61. PMID:27692431.

Genome-wide characterization of human L1 antisense promoter-driven transcripts. Criscione, S. W., Theodosakis, N., Micevic, G., Cornish, T. C., Burns, K. H., Neretti, N. and Rodic, N. 2016. BMC Genomics, 17:463. PMID:27301971.

Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Nelson, D. M., Jaber-Hijazi, F., Cole, J. J., Robertson, N. A., Pawlikowski, J. S., Norris, K. T., Criscione, S. W., Pchelintsev, N. A., Piscitello, D., Stong, N., Rai, T. S., McBryan, T., Otte, G. L., Nixon, C., Clark, W., Riethman, H., Wu, H., Schotta, G., Garcia, B. A., Neretti, N., Baird, D. M., Berger, S. L. and Adams, P. D. 2016. Genome Biol, 17:158. PMID:27457071.

Nutritional geometric profiles of insulin/IGF expression in Drosophila melanogaster. Post, S. and Tatar, M. 2016. PLoS One, 11:e0155628. PMID:27171400.

The diversity of nanos expression in echinoderm embryos supports different mechanisms in germ cell specification. Fresques, T., Swartz, S. Z., Juliano, C., Morino, Y., Kikuchi, M., Akasaka, K., Wada, H., Yajima, M. and Wessel, G. M. 2016. Evol Dev, 18:267-78. PMID:27402572.

Regeneration in bipinnaria larvae of the bat star Patiria miniata induces rapid and broad new gene expression. Oulhen, A. N., Heyland, A., Carrier, T. J., Zazueta-Novoa, V., Fresques, T., Laird, J., Onorato, T. M., Janies, D. and Wessel, G. 2016. Mech Dev, PMID:27555501.

2015

Evolutionary selection on barrier activity: Bar1 is an aspartyl protease with novel substrate specificity. Jones, S. K., Jr., Clarke, S. C., Craik, C. S. and Bennett, R. J. 2015. MBio, 6:e01604-15. PMID:26604258.

Finding a missing gene: EFG1 regulates morphogenesis in Candida tropicalis. Mancera, E., Porman, A. M., Cuomo, C. A., Bennett, R. J. and Johnson, A. D. 2015. G3 (Bethesda), 5:849-56. PMID:25758825.

Candida albicans the chameleon: transitions and interactions between multiple phenotypic states confer phenotypic plasticity. Scaduto, C. M. and Bennett, R. J. 2015. Curr Opin Microbiol, 26:102-8. PMID:26189047.

Destructin-1 is a collagen-degrading endopeptidase secreted by Pseudogymnoascus destructans, the causative agent of white-nose syndrome. O'Donoghue, A. J., Knudsen, G. M., Beekman, C., Perry, J. A., Johnson, A. D., DeRisi, J. L., Craik, C. S. and Bennett, R. J. 2015. Proc Natl Acad Sci U S A, 112:7478-83. PMID:25944934.

Effects of embryonic cyclosporine exposures on brain development and behavior. Clift, D. E., Thorn, R. J., Passarelli, E. A., Kapoor, M., LoPiccolo, M. K., Richendrfer, H. A., Colwill, R. M. and Creton, R. 2015. Behav Brain Res, 282:117-24. PMID:25591474.

RNA-binding proteins: Splicing factors and disease. Fredericks, A. M., Cygan, K. J., Brown, B. A. and Fairbrother, W. G. 2015. Biomolecules, 5:893-909. PMID:25985083.

TAF4b is required for mouse spermatogonial stem cell development. Lovasco, L. A., Gustafson, E. A., Seymour, K. A., de Rooij, D. G. and Freiman, R. N. 2015. Stem Cells, 33:1267-76. PMID:25727968.

The developmental origins of the mammalian ovarian reserve. Grive, K. J. and Freiman, R. N. 2015. Development, 142:2554-63. PMID:26243868.

Universal and domain-specific sequences in 23S-28S ribosomal RNA identified by computational phylogenetics. Doris, S. M., Smith, D. R., Beamesderfer, J. N., Raphael, B. J., Nathanson, J. A. and Gerbi, S. A. 2015. RNA, 21:1719-30. PMID:26283689.

Characterizing and controlling intrinsic biases of lambda exonuclease in nascent strand sequencing reveals phasing between nucleosomes and G-quadruplex motifs around a subset of human replication origins. Foulk, M. S., Urban, J. M., Casella, C. and Gerbi, S. A. 2015. Genome Res, 25:725-35. PMID:25695952.

The hunt for origins of DNA replication in multicellular eukaryotes. Urban, J. M., Foulk, M. S., Casella, C. and Gerbi, S. A. 2015. F1000Prime Rep, 7:30. PMID:25926981.

Pollen tube discharge completes the process of synergid degeneration that Is initiated by pollen tube-synergid interaction in Arabidopsis. Leydon, A. R., Tsukamoto, T., Dunatunga, D., Qin, Y., Johnson, M. A. and Palanivelu, R. 2015. Plant Physiol, 169:485-96. PMID:26229050.

A Drosophila model for mito-nuclear diseases generated by an incompatible interaction between tRNA and tRNA synthetase. Holmbeck, M. A., Donner, J. R., Villa-Cuesta, E. and Rand, D. M. 2015. Dis Model Mech, 8:843-54. PMID:26035388.

Dietary fatty acids and temperature modulate mitochondrial function and longevity in Drosophila. Holmbeck, M. A. and Rand, D. M. 2015. J Gerontol A Biol Sci Med Sci, 70:1343-54. PMID:25910846.

Reduced expression of MYC increases longevity and enhances healthspan. Hofmann, J. W., Zhao, X., De Cecco, M., Peterson, A. L., Pagliaroli, L., Manivannan, J., Hubbard, G. B., Ikeno, Y., Zhang, Y., Feng, B., Li, X., Serre, T., Qi, W., Van Remmen, H., Miller, R. A., Bath, K. G., de Cabo, R., Xu, H., Neretti, N. and Sedivy, J. M. 2015. Cell, 160:477-88. PMID:25619689.

Drosophila longevity assurance conferred by reduced insulin receptor substrate Chico partially requires d4eBP. Bai, H., Post, S., Kang, P. and Tatar, M. 2015. PLoS One, 10:e0134415. PMID:26252766.

Phylogenomic analyses of Echinodermata support the sister groups of Asterozoa and Echinozoa. Reich, A., Dunn, C., Akasaka, K. and Wessel, G. 2015. PLoS One, 10:e0119627. PMID:25794146.

Germ Line Versus Soma in the Transition from Egg to Embryo. Swartz, S. Z. and Wessel, G. M. 2015. Curr Top Dev Biol, 113:149-90. PMID:26358873.

2014

A critical period defined by axon-targeting mechanisms in the murine olfactory bulb. Science  Tsai, L. and Barnea, G. 2014. 344:197-200. PMID:24723611.

Convergent evolution of a fused sexual cycle promotes the haploid lifestyle. Sherwood, R. K., Scaduto, C. M., Torres, S. E. and Bennett, R. J. 2014. Nature, 506:387-90. PMID:24390351.

Sexual biofilm formation in Candida tropicalis opaque cells. Jones, S. K., Jr., Hirakawa, M. P. and Bennett, R. J. 2014. Mol Microbiol, 92:383-98. PMID:24612417.

Role of type I interferon receptor signaling on NK cell development and functions. Guan, J., Miah, S. M., Wilson, Z. S., Erick, T. K., Banh, C. and Brossay, L. 2014. PLoS One, 9:e111302. PMID:25333658.

Matrilin-3 chondrodysplasia mutations cause attenuated chondrogenesis, premature hypertrophy and aberrant response to TGF-beta in chondroprogenitor cells. Jayasuriya, C. T., Zhou, F. H., Pei, M., Wang, Z., Lemme, N. J., Haines, P. and Chen, Q. 2014. Int J Mol Sci, 15:14555-73. PMID:25196597.

High-throughput analysis of behavior in zebrafish larvae: effects of feeding. Clift, D., Richendrfer, H., Thorn, R. J., Colwill, R. M. and Creton, R. 2014. Zebrafish, 11:455-61. PMID:25153037.

The C-terminal threonine of Abeta43 nucleates toxic aggregation via structural and dynamical changes in monomers and protofibrils. Conicella, A. E. and Fawzi, N. L. 2014. Biochemistry, 53:3095-105. PMID:24773532.

Targeting TBP-associated factors in ovarian cancer. Ribeiro, J. R., Lovasco, L. A., Vanderhyden, B. C. and Freiman, R. N. 2014. Front Oncol, 4:45. PMID:24653979.

TAF4b promotes mouse primordial follicle assembly and oocyte survival. Grive, K. J., Seymour, K. A., Mehta, R. and Freiman, R. N. 2014. Developmental Biology, 392:42-51. PMID:24836512.

Dietary switch reveals fast coordinated gene expression changes in Drosophila melanogaster. Whitaker, R., Gil, M. P., Ding, F. F., Tatar, M., Helfand, S. L. and Neretti, N. 2014. Aging-Us, 6:355-68. PMID:24864304.

Interactions between pollen tube and pistil control pollen tube identity and sperm release in the Arabidopsis female gametophyte. Leydon, A. R., Chaibang, A. and Johnson, M. A. 2014. Biochem Soc Trans, 42:340-5. PMID:24646241.

Defects in pollen-tube differentiation prevent fertilization. Leydon, A. R. and Johnson, M. A. 2014. Mol Reprod Dev, 81:1. PMID:25221417.

Transcriptional landscape of repetitive elements in normal and cancer human cells. Criscione, S. W., Zhang, Y., Thompson, W., Sedivy, J. M. and Neretti, N. 2014. BMC Genomics, 15:583. PMID:25012247.

Rapamycin increases mitochondrial efficiency by mtDNA-dependent reprogramming of mitochondrial metabolism in Drosophila. Villa-Cuesta, E., Holmbeck, M. A. and Rand, D. M. 2014. J Cell Sci, 127:2282-90. PMID:24610944.

The effects of aging on the expression of Wnt pathway genes in mouse tissues. Hofmann, J. W., McBryan, T., Adams, P. D. and Sedivy, J. M. 2014. Age (Dordr), 36:9618. PMID:24488586.

Nutrient control of Drosophila longevity. Tatar, M., Post, S. and Yu, K. 2014. Trends Endocrinol Metab, 25:509-17. PMID:24685228.

The biology of the germ line in echinoderms. Wessel, G. M., Brayboy, L., Fresques, T., Gustafson, E. A., Oulhen, N., Ramos, I., Reich, A., Swartz, S. Z., Yajima, M. and Zazueta, V. 2014. Mol Reprod Dev, 81:679-711. PMID:23900765.

Isolating specific embryonic cells of the sea urchin by FACS. Juliano, C., Swartz, S. Z. and Wessel, G. 2014. Methods Mol Biol, 1128:187-96. PMID:24567215.

Selective accumulation of germ-line associated gene products in early development of the sea star and distinct differences from germ-line development in the sea urchin. Fresques, T., Zazueta-Novoa, V., Reich, A. and Wessel, G. M. 2014. Dev Dyn, 243:568-87. PMID:24038550.

Two-pore channels function in calcium regulation in sea star oocytes and embryos. Ramos, I., Reich, A. and Wessel, G. M. 2014. Development, 141:4598-609. PMID:25377554.

Deadenylase depletion protects inherited mRNAs in primordial germ cells. Swartz, S. Z., Reich, A. M., Oulhen, N., Raz, T., Milos, P. M., Campanale, J. P., Hamdoun, A. and Wessel, G. M. 2014. Development, 141:3134-42. PMID:25100654.

The biology of the germ line in echinoderms. Wessel, G. M., Brayboy, L., Fresques, T., Gustafson, E. A., Oulhen, N., Ramos, I., Reich, A., Swartz, S. Z., Yajima, M. and Zazueta, V. 2014. Mol Reprod Dev, 81:679-711. PMID:23900765.

An ancient molecular circuit specifying multipotency. Swartz, S. Z., Juliano, C. E., Raz, T., Lipson, D., Milos, P., Hamdoun, A. and Wessel, G. M. 2010. Developmental Biology, 344:514-5. PMID:WOS:000280426400382.

Isolating specific embryonic cells of the sea urchin by FACS. Juliano, C., Swartz, S. Z. and Wessel, G. 2014. Methods Mol Biol, 1128:187-96. PMID:24567215.

Deadenylase depletion protects inherited mRNAs in primordial germ cells. Swartz, S. Z., Reich, A. M., Oulhen, N., Raz, T., Milos, P. M., Campanale, J. P., Hamdoun, A. and Wessel, G. M. 2014. Development, 141:3134-42. PMID:25100654.

The biology of the germ line in echinoderms. Wessel, G. M., Brayboy, L., Fresques, T., Gustafson, E. A., Oulhen, N., Ramos, I., Reich, A., Swartz, S. Z., Yajima, M. and Zazueta, V. 2014. Mol Reprod Dev, 81:679-711. PMID:23900765.

Selective accumulation of germ-line associated gene products in early development of the sea star and distinct differences from germ-line development in the sea urchin. Fresques, T., Zazueta-Novoa, V., Reich, A. and Wessel, G. M. 2014. Dev Dyn, 243:568-87. PMID:24038550.

The biology of the germ line in echinoderms. Wessel, G. M., Brayboy, L., Fresques, T., Gustafson, E. A., Oulhen, N., Ramos, I., Reich, A., Swartz, S. Z., Yajima, M. and Zazueta, V. 2014. Mol Reprod Dev, 81:679-711. PMID:23900765.

Origin and development of the germ line in sea stars. Wessel, G. M., Fresques, T., Kiyomoto, M., Yajima, M. and Zazueta, V. 2014. Genesis, 52:367-77. PMID:24648114.

An epigenetic trap stabilizes singular olfactory receptor expression. Lyons, D. B., Allen, W. E., Goh, T., Tsai, L., Barnea, G. and Lomvardas, S. 2013. Cell, 154:325-36. PMID:23870122.

MTL-independent phenotypic switching in Candida tropicalis and a dual role for Wor1 in regulating switching and filamentation. Porman, A. M., Hirakawa, M. P., Jones, S. K., Wang, N. and Bennett, R. J. 2013. PLoS Genet, 9:e1003369. PMID:23555286.

Parasexuality and ploidy change in Candida tropicalis. Eukaryot Cell. Seervai, R. N., Jones, S. K., Jr., Hirakawa, M. P., Porman, A. M. and Bennett, R. J. 2013., 12:1629-40. PMID:24123269.

MTL-independent phenotypic switching in Candida tropicalis and a dual role for Wor1 in regulating switching and filamentation. Porman, A. M., Hirakawa, M. P., Jones, S. K., Wang, N. and Bennett, R. J. 2013. PLoS Genet, 9:e1003369. PMID:23555286.

AGG/CCT interruptions affect nucleosome formation and positioning of healthy-length CGG/CCG triplet repeats. Volle, C. B. and Delaney, S. 2013. BMC Biochem, 14:33. PMID:24261641.

Dietary and genetic effects on age-related loss of gene silencing reveal epigenetic plasticity of chromatin repression during aging. Jiang, N., Du, G., Tobias, E., Wood, J. G., Whitaker, R., Neretti, N. and Helfand, S. L. 2013. Aging (Albany NY), 5:813-24. PMID:24243774.

RNA editing regulates transposon-mediated heterochromatic gene silencing. Savva, Y. A., Jepson, J. E., Chang, Y. J., Whitaker, R., Jones, B. C., St Laurent, G., Tackett, M. R., Kapranov, P., Jiang, N., Du, G., Helfand, S. L. and Reenan, R. A. 2013. Nat Commun, 4:2745. PMID:24201902.

Increased expression of Drosophila Sir2 extends life span in a dose-dependent manner. Whitaker, R., Faulkner, S., Miyokawa, R., Burhenn, L., Henriksen, M., Wood, J. G. and Helfand, S. L. 2013. Aging (Albany NY), 5:682-91. PMID:24036492.

Genetic and biochemical tools for investigating sirtuin function in Drosophila melanogaster. Wood, J. G., Whitaker, R. and Helfand, S. L. 2013. Methods Mol Biol, 1077:57-67. PMID:24014399.

RNA editing regulates transposon-mediated heterochromatic gene silencing. Savva, Y. A., Jepson, J. E., Chang, Y. J., Whitaker, R., Jones, B. C., St Laurent, G., Tackett, M. R., Kapranov, P., Jiang, N., Du, G., Helfand, S. L. and Reenan, R. A. 2013. Nat Commun, 4:2745. PMID:24201902.

Speed dating, rejection, and finding the perfect mate: advice from flowering plants. Beale, K. M. and Johnson, M. A. 2013. Curr Opin Plant Biol, 16:590-7. PMID:24021868.

Three MYB transcription factors control pollen tube differentiation required for sperm release. Leydon, A. R., Beale, K. M., Woroniecka, K., Castner, E., Chen, J., Horgan, C., Palanivelu, R. and Johnson, M. A. 2013. Current Biology, 23:1209-14. PMID:23791732.

Preparing for explosion: Pollen tubes are capacitated by the pistil. Leydon, A. R. and Johnson, M. A. 2013. Mol Reprod Dev, 80:427. PMID:25221416.

Intellectual disability is associated with increased runs of homozygosity in simplex autism. Gamsiz, E. D., Viscidi, E. W., Frederick, A. M., Nagpal, S., Sanders, S. J., Murtha, M. T., Schmidt, M., Triche, E. W., Geschwind, D. H., State, M. W., Istrail, S., Cook, E. H., Jr., Devlin, B. and Morrow, E. M. 2013. Am J Hum Genet, 93:103-9. PMID:23830515.

Directional transport is mediated by a Dynein-dependent step in an RNA localization pathway. Gagnon, J. A., Kreiling, J. A., Powrie, E. A., Wood, T. R. and Mowry, K. L. 2013. PLoS Biol, 11:e1001551. PMID:23637574.

Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements. De Cecco, M., Criscione, S. W., Peckham, E. J., Hillenmeyer, S., Hamm, E. A., Manivannan, J., Peterson, A. L., Kreiling, J. A., Neretti, N. and Sedivy, J. M. 2013. Aging Cell, 12:247-56. PMID:23360310.

Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues. De Cecco, M., Criscione, S. W., Peterson, A. L., Neretti, N., Sedivy, J. M. and Kreiling, J. A. 2013. Aging (Albany NY), 5:867-83. PMID:24323947.

Death by transposition - the enemy within? Sedivy, J. M., Kreiling, J. A., Neretti, N., De Cecco, M., Criscione, S. W., Hofmann, J. W., Zhao, X., Ito, T. and Peterson, A. L. 2013. Bioessays, 35:1035-43. PMID:24129940.

An Incompatibility between a mitochondrial tRNA and its nuclear-encoded tRNA synthetase compromises development and fitness in Drosophila. Meiklejohn, C. D., Holmbeck, M. A., Siddiq, M. A., Abt, D. N., Rand, D. M. and Montooth, K. L. 2013. PLoS Genet, 9:e1003238. PMID:23382693.

Quantitative phosphoproteomic analysis identifies activation of the RET and IGF-1R/IR signaling pathways in neuroblastoma. DeNardo, B. D., Holloway, M. P., Ji, Q., Nguyen, K. T., Cheng, Y., Valentine, M. B., Salomon, A. and Altura, R. A. 2013. PLoS One, 8:e82513. PMID:24349301.

ERK positive feedback regulates a widespread network of tyrosine phosphorylation sites across canonical T cell signaling and actin cytoskeletal proteins in Jurkat T cells. Helou, Y. A., Nguyen, V., Beik, S. P. and Salomon, A. R. 2013. PLoS One, 8:e69641. PMID:23874979.

Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements. De Cecco, M., Criscione, S. W., Peckham, E. J., Hillenmeyer, S., Hamm, E. A., Manivannan, J., Peterson, A. L., Kreiling, J. A., Neretti, N. and Sedivy, J. M. 2013. Aging Cell, 12:247-56. PMID:23360310.

Death by transposition - the enemy within? Sedivy, J. M., Kreiling, J. A., Neretti, N., De Cecco, M., Criscione, S. W., Hofmann, J. W., Zhao, X., Ito, T. and Peterson, A. L. 2013. Bioessays, 35:1035-43. PMID:24129940.

Death by transposition - the enemy within? Sedivy, J. M., Kreiling, J. A., Neretti, N., De Cecco, M., Criscione, S. W., Hofmann, J. W., Zhao, X., Ito, T. and Peterson, A. L. 2013. Bioessays, 35:1035-43. PMID:24129940.

Meiotic gene expression initiates during larval development in the sea urchin. Yajima, M., Suglia, E., Gustafson, E. A. and Wessel, G. M. 2013. Dev Dyn, 242:155-63. PMID:23172739.

Diversity in the fertilization envelopes of echinoderms. Oulhen, N., Reich, A., Wong, J. L., Ramos, I. and Wessel, G. M. 2013. Evol Dev, 15:28-40. PMID:23331915.

Parasexuality and ploidy change in Candida tropicalis. Eukaryot Cell. Seervai, R. N., Jones, S. K., Jr., Hirakawa, M. P., Porman, A. M. and Bennett, R. J. 2013., 12:1629-40. PMID:24123269.

Neurons expressing trace amine-associated receptors project to discrete glomeruli and constitute an olfactory subsystem. Johnson, M. A., Tsai, L., Roy, D. S., Valenzuela, D. H., Mosley, C., Magklara, A., Lomvardas, S., Liberles, S. D. and Barnea, G. 2012. Proc Natl Acad Sci U S A, 109:13410-5. PMID:22837392.

Mouse natural killer cell development and maturation are differentially regulated by SHIP-1. Banh, C., Miah, S. M., Kerr, W. G. and Brossay, L. 2012. Blood, 120:4583-90. PMID:23034281.

Subcellular relocation of histone deacetylase 4 regulates growth plate chondrocyte differentiation through Ca2+/calmodulin-dependent kinase IV. Guan, Y., Chen, Q., Yang, X., Haines, P., Pei, M., Terek, R., Wei, X., Zhao, T. and Wei, L. 2012. Am J Physiol Cell Physiol, 303:C33-40. PMID:22442139.

Chemical and biological consequences of oxidatively damaged guanine in DNA. Delaney, S., Jarem, D. A., Volle, C. B. and Yennie, C. J. 2012. Free Radic Res, 46:420-41. PMID:22239655.

CAG/CTG repeats alter the affinity for the histone core and the positioning of DNA in the nucleosome. Volle, C. B. and Delaney, S. 2012. Biochemistry, 51:9814-25. PMID:23157165.

Trinucleotide repeat DNA alters structure to minimize the thermodynamic impact of 8-oxo-7,8-dihydroguanine. Volle, C. B., Jarem, D. A. and Delaney, S. 2012. Biochemistry, 51:52-62. PMID:22148399.

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo. Taggart, A. J., DeSimone, A. M., Shih, J. S., Filloux, M. E. and Fairbrother, W. G. 2012 Nat Struct Mol Biol, 19:719-21. PMID:22705790.

Gamete fusion is required to block multiple pollen tubes from entering an Arabidopsis ovule. Beale, K. M., Leydon, A. R. and Johnson, M. A. 2012. Curr Biol, 22:1090-4. PMID:22608506.

HAP2(GCS1)-dependent gamete fusion requires a positively charged carboxy-terminal domain. Wong, J. L., Leydon, A. R. and Johnson, M. A. 2010. PLoS Genet, 6:e1000882. PMID:20333238.

Gamete fusion is required to block multiple pollen tubes from entering an Arabidopsis ovule. Beale, K. M., Leydon, A. R. and Johnson, M. A. 2012. Curr Biol, 22:1090-4. PMID:22608506.

Differential ubiquitination and proteasome regulation of Ca(V)2.2 N-type channel splice isoforms. Marangoudakis, S., Andrade, A., Helton, T. D., Denome, S., Castiglioni, A. J. and Lipscombe, D. 2012. Journal of Neuroscience, 32:10365-9. PMID:22836269.

New modes of ERK feedback regulation in T cell receptor signaling revealed by quantitative phosphoproteomic analysis. Helou, Y., Nguyen, V., Beik, S., Hung, N. and Salomon, A. 2012. Journal of Immunology, 188:PMID:23874979.

Rapid detection and quantification of specific proteins by immunodepletion and microfluidic separation. Azadi, G., Gustafson, E., Wessel, G. M. and Tripathi, A. 2012. Biotechnol J, 7:1008-13. PMID:22539461.

Select microRNAs are essential for early development in the sea urchin. Song, J. L., Stoeckius, M., Maaskola, J., Friedlander, M., Stepicheva, N., Juliano, C., Lebedeva, S., Thompson, W., Rajewsky, N. and Wessel, G. M. 2012. Developmental Biology, 362:104-13. PMID:22155525.

Hyperactive BMP signaling induced by ALK2(R206H) requires type II receptor function in a Drosophila model for classic fibrodysplasia ossificans progressiva. Le, V. Q. and Wharton, K. A. 2012. Dev Dyn, 241:200-14. PMID:22174087.

Fungal mating pheromones: choreographing the dating game. Jones, S. K., Jr. and Bennett, R. J. 2011. Fungal Genet Biol, 48:668-76. PMID:21496492.

Discovery of a phenotypic switch regulating sexual mating in the opportunistic fungal pathogen Candida tropicalis. Porman, A. M., Alby, K., Hirakawa, M. P. and Bennett, R. J. 2011. Proc Natl Acad Sci U S A, 108:21158-63. PMID:22158989.

Comparative transcriptional pathway bioinformatic analysis of dietary restriction, Sir2, p53 and resveratrol life span extension in Drosophila. Antosh, M., Whitaker, R., Kroll, A., Hosier, S., Chang, C., Bauer, J., Cooper, L., Neretti, N. and Helfand, S. L. 2011. Cell Cycle, 10:904-11. PMID:21325893.

Molecular motors: directing traffic during RNA localization. Gagnon, J. A. and Mowry, K. L. 2011. Crit Rev Biochem Mol Biol, 46:229-39. PMID:21476929.

Visualization of mRNA localization in Xenopus oocytes. Gagnon, J. A. and Mowry, K. L. 2011. Methods Mol Biol, 714:71-82. PMID:21431735.

Post-translational regulation by gustavus contributes to selective Vasa protein accumulation in multipotent cells during embryogenesis. Gustafson, E. A., Yajima, M., Juliano, C. E. and Wessel, G. M. 2011. Developmental Biology, 349:440-50. PMID:21035437.

Post-translational regulation by gustavus contributes to selective Vasa protein accumulation in multipotent cells during embryogenesis. Gustafson, E. A., Yajima, M., Juliano, C. E. and Wessel, G. M. 2011. Developmental Biology, 349:440-50. PMID:21035437.

The transcriptome of a human polar body accurately reflects its sibling oocyte. Reich, A., Klatsky, P., Carson, S. and Wessel, G. 2011. J Biol Chem, 286:40743-9. PMID:21953461.

Transcriptional regulation of BK virus by nuclear factor of activated T cells. Jordan, J. A., Manley, K., Dugan, A. S., O'Hara, B. A. and Atwood, W. J. 2010. J Virol, 84:1722-30. PMID:19955309.

Identification of a cell death pathway in Candida albicans during the response to pheromone. Alby, K., Schaefer, D., Sherwood, R. K., Jones, S. K., Jr. and Bennett, R. J. 2010. Eukaryot Cell, 9:1690-701. PMID:20870881.

Identification of a cell death pathway in Candida albicans during the response to pheromone. Alby, K., Schaefer, D., Sherwood, R. K., Jones, S. K., Jr. and Bennett, R. J. 2010. Eukaryot Cell, 9:1690-701. PMID:20870881.

A protocol for the production of KLRG1 tetramer. Terrizzi, S. C., Banh, C. and Brossay, L. 2010. J Vis Exp, PMID:20068548.

Accelerated ovarian aging in the absence of the transcription regulator TAF4B in mice. Lovasco, L. A., Seymour, K. A., Zafra, K., O'Brien, C. W., Schorl, C. and Freiman, R. N. 2010. Biol Reprod, 82:23-34. PMID:19684329.

Opioid inhibition of N-type Ca2+ channels and spinal analgesia couple to alternative splicing. Andrade, A., Denome, S., Jiang, Y. Q., Marangoudakis, S. and Lipscombe, D. 2010. Nature Neuroscience, 13:1249-56. PMID:20852623.

Visualizing RNA localization in Xenopus oocytes. Gagnon, J. A. and Mowry, K. L. 2010. J Vis Exp, PMID:20075839.

Visual integration of quantitative proteomic data, pathways, and protein interactions. Jianu, R., Yu, K., Cao, L., Nguyen, V., Salomon, A. R. and Laidlaw, D. H. 2010. IEEE Trans Vis Comput Graph, 16:609-20. PMID:20467059.

Vasa genes: emerging roles in the germ line and in multipotent cells. Gustafson, E. A. and Wessel, G. M. 2010. Bioessays, 32:626-37. PMID:20586054.

DEAD-box helicases: posttranslational regulation and function. Gustafson, E. A. and Wessel, G. M. 2010. Biochem Biophys Res Commun, 395:1-6. PMID:20206133.

A conserved germline multipotency program. Juliano, C. E., Swartz, S. Z. and Wessel, G. M. 2010. Development, 137:4113-26. PMID:21098563.

Nanos functions to maintain the fate of the small micromere lineage in the sea urchin embryo. Juliano, C. E., Yajima, M. and Wessel, G. M. 2010. Developmental Biology, 337:220-32. PMID:19878662.

An ancient molecular circuit specifying multipotency. Swartz, S. Z., Juliano, C. E., Raz, T., Lipson, D., Milos, P., Hamdoun, A. and Wessel, G. M. 2010. Developmental Biology, 344:514-5. PMID:WOS:000280426400382.

Use of sea stars to study basic reproductive processes. Wessel, G. M., Reich, A. M. and Klatsky, P. C. 2010. Syst Biol Reprod Med, 56:236-45. PMID:20536323.

A conserved germline multipotency program. Juliano, C. E., Swartz, S. Z. and Wessel, G. M. 2010. Development, 137:4113-26. PMID:21098563.

Mechanism of DNA-protein cross-linking by chromium. Macfie, A., Hagan, E. and Zhitkovich, A. 2010. Chem Res Toxicol, 23:341-7. PMID:19877617.

XPA impacts formation but not proteasome-sensitive repair of DNA-protein cross-links induced by chromate. Zecevic, A., Hagan, E., Reynolds, M., Poage, G., Johnston, T. and Zhitkovich, A. 2010. Mutagenesis, 25:381-8. PMID:20410141.

Modulation of PML protein expression regulates JCV infection. Gasparovic, M. L., Maginnis, M. S., O'Hara, B. A., Dugan, A. S. and Atwood, W. J. 2009.. Virology, 390:279-88. PMID:19523662.

Fungal meiosis and parasexual reproduction--lessons from pathogenic yeast. Sherwood, R. K. and Bennett, R. J. 2009. Curr Opin Microbiol, 12:599-607. PMID:19892588.

Immunoregulatory functions of KLRG1 cadherin interactions are dependent on forward and reverse signaling. Banh, C., Fugere, C. and Brossay, L. 2009. Blood, 114:5299-306. PMID:19855082.

Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence. Reid, D. C., Chang, B. L., Gunderson, S. I., Alpert, L., Thompson, W. A. and Fairbrother, W. G. 2009. RNA, 15:2385-97. PMID:19861426.

A rapid high-throughput method for mapping ribonucleoproteins (RNPs) on human pre-mRNA. Watkins, K. H., Stewart, A. and Fairbrother, W. 2009. J Vis Exp, PMID:19956082.

The chromatin-targeting protein Brd2 is required for neural tube closure and embryogenesis. Gyuris, A., Donovan, D. J., Seymour, K. A., Lovasco, L. A., Smilowitz, N. R., Halperin, A. L., Klysik, J. E. and Freiman, R. N. 2009. Biochimica Et Biophysica Acta, 1789:413-21. PMID:19362612.

The chromatin-targeting protein Brd2 is required for neural tube closure and embryogenesis. Gyuris, A., Donovan, D. J., Seymour, K. A., Lovasco, L. A., Smilowitz, N. R., Halperin, A. L., Klysik, J. E. and Freiman, R. N. 2009. Biochimica Et Biophysica Acta, 1789:413-21. PMID:19362612.

Long-lived Indy and calorie restriction interact to extend life span. Wang, P. Y., Neretti, N., Whitaker, R., Hosier, S., Chang, C., Lu, D., Rogina, B. and Helfand, S. L. 2009. Proc Natl Acad Sci U S A, 106:9262-7. PMID:19470468.

Expressing the diphtheria toxin A subunit from the HAP2(GCS1) promoter blocks sperm maturation and produces single sperm-like cells capable of fertilization. Frank, A. C. and Johnson, M. A. 2009. Plant Physiol, 151:1390-400. PMID:19734264

The inhibition of neuronal calcium ion channels by trace levels of yttrium released from carbon nanotubes. Jakubek, L. M., Marangoudakis, S., Raingo, J., Liu, X., Lipscombe, D. and Hurt, R. H. 2009. Biomaterials, 30:6351-7. PMID:19698989.

VISIONS: the art of science. Gagnon, J. A. and Mowry, K. L. 2009. Mol Reprod Dev, 76:1115. PMID:19834979.

A new approach for quantitative phosphoproteomic dissection of signaling pathways applied to T cell receptor activation. Nguyen, V., Cao, L., Lin, J. T., Hung, N., Ritz, A., Yu, K., Jianu, R., Ulin, S. P., Raphael, B. J., Laidlaw, D. H., Brossay, L. and Salomon, A. R. 2009. Mol Cell Proteomics, 8:2418-31. PMID:19605366.

An evolutionary transition of Vasa regulation in echinoderms. Juliano, C. E. and Wessel, G. M. 2009. Evol Dev, 11:560-73. PMID:19754712.

WRN helicase promotes repair of DNA double-strand breaks caused by aberrant mismatch repair of chromium-DNA adducts. Zecevic, A., Menard, H., Gurel, V., Hagan, E., DeCaro, R. and Zhitkovich, A. 2009. Cell Cycle, 8:2769-78. PMID:19652551.

Direct correlation between sialic acid binding and infection of cells by two human polyomaviruses (JC virus and BK virus).Dugan, A. S., Gasparovic, M. L. and Atwood, W. J. 2008. J Virol, 82:2560-4. PMID:18094176.

Human alpha-defensins inhibit BK virus infection by aggregating virions and blocking binding to host cells Dugan, A. S., Maginnis, M. S., Jordan, J. A., Gasparovic, M. L., Manley, K., Page, R., Williams, G., Porter, E., O'Hara, B. A. and Atwood, W. J. 2008.. J Biol Chem, 283:31125-32. PMID:18782756.

Human alpha-defensins inhibit BK virus infection by aggregating virions and blocking binding to host cells. Dugan, A. S., Maginnis, M. S., Jordan, J. A., Gasparovic, M. L., Manley, K., Page, R., Williams, G., Porter, E., O'Hara, B. A. and Atwood, W. J. 2008. J Biol Chem, 283:31125-32. PMID:18782756.

Microtubule motor protein Kar3 is required for normal mitotic division and morphogenesis in Candida albicans. Sherwood, R. K. and Bennett, R. J. 2008. Eukaryot Cell, 7:1460-74. PMID:18586948.

PTB/hnRNP I is required for RNP remodeling during RNA localization in Xenopus oocytes. Lewis, R. A., Gagnon, J. A. and Mowry, K. L. 2008. Molecular and Cellular Biology, 28:678-86. PMID:18039852.

Multiple kinesin motors coordinate cytoplasmic RNA transport on a subpopulation of microtubules in Xenopus oocytes. Messitt, T. J., Gagnon, J. A., Kreiling, J. A., Pratt, C. A., Yoon, Y. J. and Mowry, K. L. 2008. Dev Cell, 15:426-36. PMID:18771961.

Polycomb group gene expression in the sea urchin. Gustafson, E. A. and Wessel, G. M. 2008. Dev Dyn, 237:1851-61. PMID:18521949.

Vasa protein expression is restricted to the small micromeres of the sea urchin, but is inducible in other lineages early in development. Voronina, E., Lopez, M., Juliano, C. E., Gustafson, E., Song, J. L., Extavour, C., George, S., Oliveri, P., McClay, D. and Wessel, G. 2008. Developmental Biology, 314:276-86. PMID:18191830.

Vasa protein expression is restricted to the small micromeres of the sea urchin, but is inducible in other lineages early in development. Voronina, E., Lopez, M., Juliano, C. E., Gustafson, E., Song, J. L., Extavour, C., George, S., Oliveri, P., McClay, D. and Wessel, G. 2008. Developmental Biology, 314:276-86. PMID:18191830.

Identification of amino acid residues in BK virus VP1 that are critical for viability and growth. Dugan, A. S., Gasparovic, M. L., Tsomaia, N., Mierke, D. F., O'Hara, B. A., Manley, K. and Atwood, W. J. 2007. J Virol, 81:11798-808. PMID:17699578.

Ovarian granulosa cell survival and proliferation requires the gonad-selective TFIID subunit TAF4b. Voronina, E., Lovasco, L. A., Gyuris, A., Baumgartner, R. A., Parlow, A. F. and Freiman, R. N. 2007. Developmental Biology, 303:715-26. PMID:17207475.

Quantitative time-resolved phosphoproteomic analysis of mast cell signaling. Cao, L., Yu, K., Banh, C., Nguyen, V., Ritz, A., Raphael, B. J., Kawakami, Y., Kawakami, T. and Salomon, A. R. 2007. Journal of Immunology, 179:5864-76. PMID:17947660.

Germ line determinants are not localized early in sea urchin development, but do accumulate in the small micromere lineage. Juliano, C. E., Voronina, E., Stack, C., Aldrich, M., Cameron, A. R. and Wessel, G. M. 2006. Developmental Biology, 300:406-15. PMID:16970939.

The human polyomavirus, JCV, uses serotonin receptors to infect cells. Elphick, G. F., Querbes, W., Jordan, J. A., Gee, G. V., Eash, S., Manley, K., Dugan, A., Stanifer, M., Bhatnagar, A., Kroeze, W. K., Roth, B. L. and Atwood, W. J. 2004 Science, 306:1380-3. PMID:15550673.

Early events in the life cycle of JC virus as potential therapeutic targets for the treatment of progressive multifocal leukoencephalopathy. Baum, S., Ashok, A., Gee, G., Dimitrova, S., Querbes, W., Jordan, J. and Atwood, W. J. 2003. J Neurovirol, 9 Suppl 1:32-7. PMID:12709869.