Sendurai Mani

Sendurai Mani
Professor of Pathology and Laboratory Medicine
Associate Director for Translational Oncology, Legorreta Cancer Center
Director, Translational Research Disease Groups
Director, Cancer Stem Cell/TIME Center


The Mani lab studies how cancer cells escape the immune system and develop resistance to treatments, metastasis, and tumor relapse. We use a combination of cell biology, immune biology, single-cell and spatial transcriptomics, in vitro and in vivo mouse modeling, and multiplex immunofluorescence techniques to address these important questions.