NIOSH Pocket Guide to Chemical Hazards

Methoxyflurane CAS 76-38-0
Synonyms & Trade Names
2,2-Dichloro-1,1-difluoroethyl methyl ether; 2,2-Dichloro-1,1-difluoro-1-methoxyethane; Methoflurane; Methoxyfluorane; Penthrane
DOT ID & Guide
NIOSH REL*: C 2 ppm (13.5 mg/m3) [60-minute] [*Note: REL for exposure to waste anesthetic gas.]
OSHA PEL: none
IDLH N.D. Conversion 1 ppm = 6.75 mg/m3
Physical Description
Colorless liquid with a fruity odor. [inhalation anesthetic]
MW: 165.0
BP: 220°F
FRZ: -31°F
Sol: Slight
VP: 23 mmHg
IP: ?

Sp.Gr(77°F): 1.42
Fl.P: ?
UEL: ?
LEL(176°F): 7%

Combustible Liquid
Incompatibilities & Reactivities
None reported
Measurement Methods
None available
Personal Protection & Sanitation
Skin: No recommendation
Eyes: Prevent eye contact
Wash skin: No recommendation
Remove: When wet or contaminated
Change: No recommendation

First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations To be added later
Exposure Routes inhalation, ingestion, skin and/or eye contact
Symptoms Irritation eyes; central nervous system depression, analgesia, anesthesia, convulsions, respiratory depression; liver, kidney injury; in animals: reproductive, teratogenic effects
Target Organs Eyes, central nervous system, liver, kidneys, reproductive system