NIOSH Pocket Guide to Chemical Hazards

4,4'-Methylenebis(2-chloroaniline) CAS 101-14-4
CH2(C6H4ClNH2)2 RTECS CY1050000
Synonyms & Trade Names
DACPM; 3,3'-Dichloro-4,4'-diaminodiphenylmethane; MBOCA; 4,4'-Methylenebis(o-chloro aniline); 4,4'-Methylenebis(2-chlorobenzenamine); MOCA
DOT ID & Guide
NIOSH REL: Ca TWA 0.003 mg/m3 [skin] See Appendix A
OSHA PEL†: none
IDLH Ca [N.D.] Conversion
Physical Description
Tan-colored pellets or flakes with a faint, amine-like odor.
MW: 267.2
BP: ?
MLT: 230°F
Sol: Slight
VP(77°F): 0.00001 mmHg
IP: ?

Sp.Gr: 1.44
Fl.P: ?
UEL: ?
LEL: ?

Incompatibilities & Reactivities
Chemically-active metals (e.g., potassium, sodium, magnesium, zinc)
Measurement Methods
OSHA 24, 71
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated/Daily
Remove: When wet or contaminated
Change: Daily
Provide: Eyewash, Quick drench
First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap flush immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having a high-efficiency particulate filter/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Hematuria (blood in the urine), cyanosis, nausea, methemoglobinemia, kidney irritation; [potential occupational carcinogen]
Target Organs Liver, blood, kidneys

Cancer Site [in animals: liver, lung & bladder tumors]