NIOSH Pocket Guide to Chemical Hazards

p-Nitrochlorobenzene CAS 100-00-5
ClC6H4NO2 RTECS CZ1050000
Synonyms & Trade Names
p-Chloronitrobenzene, 4-Chloronitrobenzene, 1-Chloro-4-nitrobenzene, 4-Nitrochlorobenzene, PCNB, PNCB
DOT ID & Guide
1578 152
NIOSH REL: Ca See Appendix A [skin]
OSHA PEL: TWA 1 mg/m3 [skin]
IDLH Ca [100 mg/m3] Conversion
Physical Description
Yellow, crystalline solid with a sweet odor.
MW: 157.6
BP: 468°F
MLT: 182°F
Sol: Slight
VP(86°F): 0.2 mmHg
IP: 9.96 eV

Sp.Gr: 1.52
Fl.P: 261°F
UEL: ?
LEL: ?

Solid that does not burn, or burns with difficulty.
Incompatibilities & Reactivities
Strong oxidizers, alkalis
Measurement Methods
NIOSH 2005
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated/Daily
Remove: When wet or contaminated
Change: Daily
Provide: Eyewash, Quick drench
First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator with a high-efficiency particulate filter/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Anoxia; unpleasant taste; anemia; methemoglobinemia; in animals: hematuria (blood in the urine); spleen, kidney, bone marrow changes; reproductive effects; [potential occupational carcinogen]
Target Organs Blood, liver, kidneys, cardiovascular system, spleen, bone marrow, reproductive system

Cancer Site [in animals: vascular & liver tumors]