- Royce Fellowship
Kaitlyn
Tracy
Concentration
Biochemistry; French Literature
Award Year
2013
Nanopieces as a high-efficiency, low-toxicity delivery vehicle for siRNA
Faculty Sponsor: Dr. Qian Chen
Working in Dr. Qian Chen’s Orthopaedic Lab at Brown University, Kaitlyn investigated the efficacy of novel Nanopieces as an siRNA delivery vehicle. Conventional siRNA delivery methods often induce high levels of cytotoxicity due to their lipid-based composition. The biomimetic design and small size of nanotubes will allow the Nanopiece, bound with siRNA, to penetrate hard-to-transfect, matrix-rich cells with minimal induced cytotoxicity, prerequisites for successful therapeutic application.