News

Recent Intra-CBME Collaborative Publications - Fleming/Jay & Shukla/Tripathi

October 25, 2017
Celinda Kofron
Jay, Fleming, and students

Gregory Jay and Braden Fleming discuss their research with their students.

Anita Shukla & Christina Bailey

Anita Shukla and Christina Bailey discuss their research.

Our collaborative research environment often leads to intra-CBME joint publications.

Earlier this year, Gregory Jay and Braden Fleming collaborated on two studies. "Reduction of friction by recombinant human proteoglycan 4 in IL-1α stimulated bovine cartilage explants," published in the Journal of Orthopaedic Research, supported the therapeutic value of proteoglycan-4 (PRG4) in reducing friction in transient inflammatory conditions. Recent PhD graduate Katherine Larson was the first author. "Intra-articular Recombinant Human Proteoglycan 4 Mitigates Cartilage Damage After Destabilization of the Medial Meniscus in the Yucatan Minipig," published in The American Journal of Sports Medicine, demonstrated that an intra-articular injection regimen of recombinant human lubricin (rhPRG4) may attenuate cartilage damage after meniscal injury. Recent PhD graduate Kimberly Waller was the lead author.

Last month, Anita Shukla and Anubhav Tripathi co-authored a study to elucidate the effects of flow and concentration on the formation of supported lipid bilayers (SLBs).  SLBs can be used to model cell membranes, but Shukla, Tripathi, and PhD candidate Christina Bailey seek to advance the biomedical applications of SLBs through a better understanding of bilayer self-assembly. Their study "Effects of Flow and Bulk Vesicle Concentration on Supported Lipid Bilayer Formation" was published in Langmuir.